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NYCC Physiopathology > Immunoglobulins > Flashcards

Immunoglobulins Flashcards

1
Q

What is your natural or innate immunity?

A
  • Inflammatory response that is non specific and lacks memory
  • Does not require prior exposure to the antigen
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2
Q

Which immunity is your inflammatory response?

A

Natural/innate

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3
Q

What is your acquired or adaptive immunity?

A

A specific response to a specific antigen that requires a sensitizing exposure and is magnified by subsequent exposures

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4
Q

What are the primary immunoglobulins?

A

IgA
IgG
IgM
IgD
IgE

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5
Q

What is the primary function of IgA?

A
  • Protection of body surfaces exposed to foreign organisms and substances
  • First line of defense
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6
Q

Where are IgA immunoglobulins located?

A
  • Mucosal surfaces such as the nose, respiratory tract, GI tract, ears, eyes, and vagina
  • Saliva and tears
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7
Q

What is the primary function of IgG?

A

Fighting of bacterial and viral infections as well as fetal immunity

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8
Q

Where are IgG immunoglobulins located?

A

Body fluids

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9
Q

What is smallest and most abundant antibody in the body?

A

IgG

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10
Q

What is the largest antibody?

A

IgM

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11
Q

Where are IgM antibodies found?

A

Blood and lymph fluid

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12
Q

What is the first antibody produced in response to an infection?

A

IgM

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13
Q

What antibody is seen first in an early infection? Second?

A

IgM first and then IgG

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14
Q

Where are IgD antibodies found?

A

Tissue lining cavities in the body

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15
Q

What is the function of IgD antibodies?

A

Not well defined but play a role in allergic reactions such as milk, medication, and poisons

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16
Q

Where are IgE antibodies located?

A

Lungs, skin, and mucous membranes

17
Q

What is the function of IgE antibodies?

A

Protect the body against foreign substances such as pollen, fungus spores, and animal dander

18
Q

In people with allergies, you often see high levels of _______ antibodies?

A

IgE

19
Q

The presence of what immunoglobulin indicates acute infection?

A

IgM

20
Q

The presence of what immunoglobulin indicates chronic infection?

A

IgG

21
Q

What antibody is involved in a type one hypersensitivity reaction?

A

IgE

22
Q

What antibodies are involved in a type two hypersensitivity reaction?

A

IgG and IgM

23
Q

What antibodies are involved in a type three hypersensitivity reaction?

A

IgG and IgM

24
Q

What is the only acquired (secondary) immunodeficiency disease (that we know of)?

A

HIV/AIDS

25
Q

What hypersensitivity reactions are triggered by heightened levels of IgM and IgG antibodies?

A

Type 2 and type 3 hypersensitivity

NYCC Physiopathology (28 decks)

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