Immunoglobulins Flashcards
What is your natural or innate immunity?
- Inflammatory response that is non specific and lacks memory
- Does not require prior exposure to the antigen
Which immunity is your inflammatory response?
Natural/innate
What is your acquired or adaptive immunity?
A specific response to a specific antigen that requires a sensitizing exposure and is magnified by subsequent exposures
What are the primary immunoglobulins?
IgA
IgG
IgM
IgD
IgE
What is the primary function of IgA?
- Protection of body surfaces exposed to foreign organisms and substances
- First line of defense
Where are IgA immunoglobulins located?
- Mucosal surfaces such as the nose, respiratory tract, GI tract, ears, eyes, and vagina
- Saliva and tears
What is the primary function of IgG?
Fighting of bacterial and viral infections as well as fetal immunity
Where are IgG immunoglobulins located?
Body fluids
What is smallest and most abundant antibody in the body?
IgG
What is the largest antibody?
IgM
Where are IgM antibodies found?
Blood and lymph fluid
What is the first antibody produced in response to an infection?
IgM
What antibody is seen first in an early infection? Second?
IgM first and then IgG
Where are IgD antibodies found?
Tissue lining cavities in the body
What is the function of IgD antibodies?
Not well defined but play a role in allergic reactions such as milk, medication, and poisons
Where are IgE antibodies located?
Lungs, skin, and mucous membranes
What is the function of IgE antibodies?
Protect the body against foreign substances such as pollen, fungus spores, and animal dander
In people with allergies, you often see high levels of _______ antibodies?
IgE
The presence of what immunoglobulin indicates acute infection?
IgM
The presence of what immunoglobulin indicates chronic infection?
IgG
What antibody is involved in a type one hypersensitivity reaction?
IgE
What antibodies are involved in a type two hypersensitivity reaction?
IgG and IgM
What antibodies are involved in a type three hypersensitivity reaction?
IgG and IgM
What is the only acquired (secondary) immunodeficiency disease (that we know of)?
HIV/AIDS
What hypersensitivity reactions are triggered by heightened levels of IgM and IgG antibodies?
Type 2 and type 3 hypersensitivity
