final pt 5 draft Flashcards
what are 2 non-inflammatory vascular disorders?
- Monkeberg Medial Sclerosis
- Raynaud phenomenon
what are the inflammatory vascular disorders?
- takayasu arteritis
- polarteritis nodosa
- Allergic Granulomatous and angitis (Churg-Strauss)
- Temporal Arteritis
- Kawasaki disease
- Wegeners Granulomatosis
- Thromoangitis Obliterans (Buergers)
- Behcet
what refers to a degenerative calcification of the tunica media of large and medium sized muscular arteries?
Monkeberg medial sclerosis
what age is monkeburg usually seen in?
older individual
Mokeberg medial sclerosis usually occurs in what arteries?
arteries of the upper and lower extremities (may cause post. knee pain)
T/F: Monkeberg medial sclerosis is very similar to atherosclerosis
F
it is distinct from atherosclerosis
-ordinarily does NOT lead to a clinical presentation per se
atherosclerosis is of the tunica intima where monkeberg is of the tunica media
T/F: there is major luminal narrowing in Monkeberg medial sclerosis
F: there is none
what is the etiology of Monkeberg?
unknown
is Monkeberg inflammatory or non?
non inflammatory
what is paroxysmal pallor or cyanosis of the digits of the hands or feet?
Raynaud phenomenon
what is Raynauds usually caused by?
due to cold induced vasoconstriction
what is the color change sequence in Raynauds?
white- blue- Red
T/F: Raynauds reflects an exaggeration of normal central and vasomotor responses to cold or emotion
T
what is the prognosis of RP?
- usually benign
- long-standing cases may show signs of atrophy of skin, subcutaneous tissue and muscles
T/F: ulcerations and gangrene are rare for RP
T
what is the difference between primary and secondary Raynaud Phenomenon?
- primary = you just have it
secondary = some primary disease triggers RP
what refers to the inflammation of walls of vessels (all sizes and types)?
inflammatory vasculitides
how can we classify inflammatory Vasculitis?
based on pathogenesis or etiology
what are different ways you get vasculitis?
infection
immunologic
unknown
what is the clinical presentation of vasculitis?
often a result of vessel lumen narrowing/ obliteration/ dilation / thrombosis
what therapy is usually used to treat vasculitis?
Responsive to steroid/immunosuppressive-therapy
what kind of tests will suspected Vasculitis patients have performed?
inflammatory/ autoimmune panel
what is tested in an inflammatory/autoimmune panel?
ESR
CRP
RF
ANA
ANCA
Specific Ig’s
what does ESR stand for an what is it?
- Erythrocyte sedimentation rate
- non specific indication of inflammation when elevated