IMMUNO Flashcards

1
Q

APC stimulate IL-12to what

A

TH1 cells

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2
Q

Th1 releases what to stimulate macrophages

A

IFN-g

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3
Q

TH2 secretes

A

IL-4
IL-5
IL-10
IL-13

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4
Q

differentiation of TH2 cells is by

A

IL_4

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5
Q

differentiation of TH1 cells is by

A

IFN-y and IL-12

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6
Q

two anti-inflammatory cytokines

A

IL-10 and TGF-B

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7
Q

two things needed for t cell activation

A

B cells activation and class switching

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8
Q

isotope switching is stimulated by

A

CD40L

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9
Q

acute phase reactants are induced by

A

IL-6

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10
Q

C3a, 4a, 5a are for

A

anaphylaxis

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11
Q

C3b is for

A

opsonization

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12
Q

tow main things involved in opsonization ( gets bacteria ready to be eaten )

A

C3b and IgG

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13
Q

two inhibitors that help prevent complement activation on self cells

A

C1 esterase inhibitor

DAF ( decay-accelerating factor)

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14
Q

C5-C9 deficiency increases the risk of

A

Neisseria bacteremia

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15
Q

C3 deficiency increases the risk for

A

type 3 Hyper sensitivity reaction

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16
Q

CD16 represents

A

NK cells

17
Q

CD14 represents

A

Macrophages

18
Q

anti glutamic acid decarboxylase

A

type 1 diabetes

19
Q

anti-Jo-1
anti SRP
anti-MI-2

A

Polymyositis dermatomyositis

20
Q

antimicrosomal

antithyroglobulin

A

Hashimoto

21
Q

antimitochondrial

A

primary biliary cirrhosis

22
Q

anti phospholipase A2

A

primary membranous nephropathy

23
Q

anti smooth

A

autoimmune hepatitis

24
Q

anti-U1 RNP

A

mixed connective tissue disorder

25
Q

A lack of negative selection in the thymus is known as what

A

Autoimmune polyendocrine syndrome 1