9/30 Flashcards

1
Q

here are some symptoms, tell me the disease

  • girl with a mutation in MECP2
  • loss of motor and verbal skills at age 5 months
  • movement of the hands that doesn’t stop
  • decrease in head circumference
A

Rett Syndrome

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2
Q

what is in the walls of a pseudocyst in the pancreas from acute pancreatitis

A

granulation tissue and fibrosis

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3
Q

immediate treatment for panic attacks

A

benzodiazepines

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4
Q

long term treatment for panic attacks

A

SSRI/SNRI and cognitive behavioral therapy

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5
Q

what happens to the FMR1 gene in patients with fragile x

A

it is methylated and inactivated

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6
Q

describe imprinting

A

gene expression only comes from one parent instead of two

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7
Q

what is Ramelton

A

a melatonin agonist used for insomnia safe for the use of the elderly

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8
Q

what kind of drugs are used to treat psoriasis

A

vitamin D analog drugs

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9
Q

vitamin d analogy drugs used to treat psoriasis

A

Calcitriol
Tacalcitol
Calicpotriene

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10
Q

what is the MOA of vitamin D analogues

A

bind to the vitamin D receptor and inhibit keratinocyte proliferation

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11
Q

cyclosporine is used for what three things

A

RA
organ rejection
psoriasis

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12
Q

what drug treats moderate to severe psoriasis

A

etanercept

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13
Q

monoclonal ab that is used to target IL-12 and IL-23 in psoriasis, inhibiting the activation of TH1 and TH 17 cells

A

Ustekinumab `

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14
Q

what psoriasis drug blocks a nuclear transcription factor

A

calcitriol
tacalcitol
calcpotriene

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15
Q

what is found in sweet peas that can inhibit lyse oxidase making it look similar to myxomatous cystic degeneration in the media of the aorta

A

B-aminopropionitrile

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16
Q

what causes maternal insulin to rise during the second and third trimester

A

human placental lactogen

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17
Q

what is dipyridamole

A

a vasodilator of coronary vessels

18
Q

how can adenosine and dipyridamole cause Coronary Steal Syndrome

A

because it will reduce blood flow in ischemic areas by vasodilating the arteries in nonischemic areas

19
Q

what is the haldane effect

A

when hypoxia is corrected and HBg used to have high affinity for CO2, now has low affinity for it and it increases in the system ( patients with COPD who get oxygen too much )

20
Q

what is ephelidies

A

freckles

21
Q

what is the major breakdown product of 5HT

A

5 hydroxyindoleacetic acid

22
Q

aortic stenosis is a harsh ejection type systolic murmur that is heard best at

A

the base of the heart

23
Q

brief psychotic disorder never exceeds

A

one month

24
Q

ringed shaped RBC inclusion

A

malaria

25
Q

cross “Maltese” shipped RBC inclusion

A

babeosis

26
Q

low levels of AFP
high levels of Inhibin A and B-hCG
associated with

A

downsyndrome

27
Q

three diseases associated with HLA class 2

A

RA
Diabetes type 1
celiac disease

28
Q

escitalopram is what kind of drug

A

SSRI

29
Q

sertraline is what kind of drug

A

SSRI

30
Q

Venlafaxine is what kind of drug

A

SNRI

31
Q

what does Rifaximin do

A

decreases intraluminal production of ammonia and is used to treat hepatic encephalopathy

32
Q

two things that lead to hepatic encephalopathy

A

eating a large steak and Gi bleeding, increase nitrogenous products

33
Q

treatment for obsessive compulsive disorder

A

SSRI

34
Q

impaired absorption in what amino acids is seen in Cysteinuria

A
COLA
cysteine
ornithine
lysine
arginine
35
Q

test between two categorical variable

A

chi sqaure

36
Q

test between two means

A

t test

37
Q

what is the most common cause of death in people with freidrich ataxia

A

hypertrophic cardiomyopathy

38
Q

what can cause contraction in the smooth muscle cells of the sphincter of odds causing common bile duct and gallbladder obstruction

A

opioids

39
Q

toxic megacolon can be associate with what two things

A

c. diff and ulcerative colitis

40
Q

what kind of murmur increases with inspiration

A

tricuspid regurgitation

41
Q

chest x ray that looks way worse then how the patient is presenting

A

Mycoplasma Pneumonia