9/30

Question 1

here are some symptoms, tell me the disease

• girl with a mutation in MECP2
• loss of motor and verbal skills at age 5 months
• movement of the hands that doesn’t stop
• decrease in head circumference

Answer 1

Rett Syndrome

Question 2

what is in the walls of a pseudocyst in the pancreas from acute pancreatitis

Answer 2

granulation tissue and fibrosis

Question 3

immediate treatment for panic attacks

Answer 3

benzodiazepines

Question 4

long term treatment for panic attacks

Answer 4

SSRI/SNRI and cognitive behavioral therapy

Question 5

what happens to the FMR1 gene in patients with fragile x

Answer 5

it is methylated and inactivated

Question 6

describe imprinting

Answer 6

gene expression only comes from one parent instead of two

Question 7

what is Ramelton

Answer 7

a melatonin agonist used for insomnia safe for the use of the elderly

Question 8

what kind of drugs are used to treat psoriasis

Answer 8

vitamin D analog drugs

Question 9

vitamin d analogy drugs used to treat psoriasis

Answer 9

Calcitriol
Tacalcitol
Calicpotriene

Question 10

what is the MOA of vitamin D analogues

Answer 10

bind to the vitamin D receptor and inhibit keratinocyte proliferation

Question 11

cyclosporine is used for what three things

Answer 11

RA
organ rejection
psoriasis

Question 12

what drug treats moderate to severe psoriasis

Answer 12

etanercept

Question 13

monoclonal ab that is used to target IL-12 and IL-23 in psoriasis, inhibiting the activation of TH1 and TH 17 cells

Answer 13

Ustekinumab `

Question 14

what psoriasis drug blocks a nuclear transcription factor

Answer 14

calcitriol
tacalcitol
calcpotriene

Question 15

what is found in sweet peas that can inhibit lyse oxidase making it look similar to myxomatous cystic degeneration in the media of the aorta

Answer 15

B-aminopropionitrile

Question 16

what causes maternal insulin to rise during the second and third trimester

Answer 16

human placental lactogen

Question 17

what is dipyridamole

Answer 17

a vasodilator of coronary vessels

Question 18

how can adenosine and dipyridamole cause Coronary Steal Syndrome

Answer 18

because it will reduce blood flow in ischemic areas by vasodilating the arteries in nonischemic areas

Question 19

what is the haldane effect

Answer 19

when hypoxia is corrected and HBg used to have high affinity for CO2, now has low affinity for it and it increases in the system ( patients with COPD who get oxygen too much )

Question 20

what is ephelidies

Answer 20

freckles

Question 21

what is the major breakdown product of 5HT

Answer 21

5 hydroxyindoleacetic acid

Question 22

aortic stenosis is a harsh ejection type systolic murmur that is heard best at

Answer 22

the base of the heart

Question 23

brief psychotic disorder never exceeds

Answer 23

one month

Question 24

ringed shaped RBC inclusion

Answer 24

malaria

Question 25

cross "Maltese" shipped RBC inclusion

Answer 25

babeosis

Question 26

low levels of AFP high levels of Inhibin A and B-hCG associated with

Answer 26

downsyndrome

Question 27

three diseases associated with HLA class 2

Answer 27

RA Diabetes type 1 celiac disease

Question 28

escitalopram is what kind of drug

Answer 28

SSRI

Question 29

sertraline is what kind of drug

Answer 29

SSRI

Question 30

Venlafaxine is what kind of drug

Answer 30

SNRI

Question 31

what does Rifaximin do

Answer 31

decreases intraluminal production of ammonia and is used to treat hepatic encephalopathy

Question 32

two things that lead to hepatic encephalopathy

Answer 32

eating a large steak and Gi bleeding, increase nitrogenous products

Question 33

treatment for obsessive compulsive disorder

Answer 33

SSRI

Question 34

impaired absorption in what amino acids is seen in Cysteinuria

Answer 34

``` COLA cysteine ornithine lysine arginine ```

Question 35

test between two categorical variable

Answer 35

chi sqaure

Question 36

test between two means

Answer 36

t test

Question 37

what is the most common cause of death in people with freidrich ataxia

Answer 37

hypertrophic cardiomyopathy

Question 38

what can cause contraction in the smooth muscle cells of the sphincter of odds causing common bile duct and gallbladder obstruction

Answer 38

opioids

Question 39

toxic megacolon can be associate with what two things

Answer 39

c. diff and ulcerative colitis

Question 40

what kind of murmur increases with inspiration

Answer 40

tricuspid regurgitation

Question 41

chest x ray that looks way worse then how the patient is presenting

Answer 41

Mycoplasma Pneumonia