Immune and lymphatic system Flashcards

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1
Q

What is the immune system?

A

The immune system is our body’s defense system against harmful invaders like bacteria, viruses, and other pathogens. It’s made up of different cells, tissues, and organs that
work together to recognize and attack anything that might cause us harm.

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2
Q

What does the immunes sytstem consist of?

A

There are two main parts:
the innate immune system, which isthe first line of defense and responds quickly to general threats. And the adaptive immune system, which takes longer to respond but is
more targeted and remembers specific invaders for future protection. Together, these parts help keep us
healthy by identifying and eliminating harmful substances.

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3
Q

Type of white blood cells?

A

lymphocytes, monocytes, neutrophils, basophils, eosinophils.

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4
Q

Neutrophil function?

A

Function: First responders to infection; they engulf
and digest bacteria and fungi.

Characteristics: Make up about 50-70% of WBCs;
have a multi-lobed nucleus.

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5
Q

Lymphocyte function?

A

B cells: Produce antibodies that target specific
pathogens.

T cells: Destroy infected or cancerous cells and
help regulate immune responses.

Natural Killer (NK) cells: Attack virus-infected
and tumor cells.

Comprise about 20-40% of
WBCs; large nucleus with little cytoplasm.

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6
Q

Monocyte function?

A

Function: Differentiate into macrophages and
dendritic cells; they engulf pathogens and
present antigens to T cells.

Characteristics: About 2-8% of WBCs; largest
type of WBC, with a kidney-shaped nucleus.

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7
Q

Basophil function:

A

Function: Release histamine during allergic
reactions and inflammation.

Characteristics: Least common, about
0.5-1% of WBCs; have large granules that
obscure the nucleus.

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8
Q

Eosinophil function:

A

Function: Fight parasitic infections and are
involved in allergic reactions.

Characteristics: Make up about 1-4% of WBCs;
have a bi-lobed nucleus and granules in the
cytoplasm.

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9
Q

How are antibodies structured?

A

Y-shaped proteins with four chains (two heavy, two light); contains variable and
constant regions.

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10
Q

What are the antibodies types?

A

IgA: Found in mucosal areas and secretions; protects mucosal surfaces.

IgM: First produced during infection; forms complexes and activates complement.

IgE: Involved in allergic reactions and fights parasites.

IgD: Located on B cells; role in B cell activation is less understood.

AMED

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11
Q

What is the lymphatic system?

A

is the system of vessels, cells, and organs that carries excess fluids to the bloodstream and filters pathogens from the blood.

It consists of a network of lymphatic vessels that carry a clear fluid called lymph directionally towards the heart.

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12
Q

How does the lymphatic system function as immune defense?

A

The first and probably most well-known function of the lymphatic system is defense against invading microorganisms and disease.
Lymph nodes and other lymphatic organs filter the lymph to remove microorganisms and other foreign particles.
Lymphatic organs contain B lymphocytes, T lymphocyte, and Phagocytes that destroy invading organisms.

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13
Q

How does the lymphatic system function in fat absorption?

A

The third function of the lymphatic system is the absorption of fats and fat-soluble vitamin from the digestive system and the subsequent transport of these substances to the venous circulation. The mucosa that lines the small intestine is covered with fingerlike projections called villi.
There are blood capillaries and special lymph capillaries, called lacteals in the center of each villus. The blood capillaries absorb most nutrients, but the fats and fat-soluble vitamins are absorbed by the lacteals. The lymph in the lacteals has a milky appearance due to its high fat content and is called chyle.

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14
Q

Functions of the lymphatic system?

A

immune defense, fluid balance, fat absorption.

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15
Q

What are the components of the lymphatic system?

A

lymph nodes, lymph vessels, lymph capillaries, lymph fluid, thymus, speel.

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16
Q

What are the lymph capillaries?

A

Tiny, thin-walled vessels located
throughout body tissues that absorb
excess fluid, waste, and pathogens from
spaces between cells.

Starting point of the lymphatic system,
where lymph is first collected before
moving into larger lymph vessels.

17
Q

What are the lymph vessels?

A

Network of thin tubes similar to blood vessels,
carrying lymph fluid

One-way flow system that moves lymph fluid
towards the heart.

18
Q

What are the lymph nodes?

A

Small, bean-shaped filters located along lymph
vessels.

Trap and destroy pathogens and foreign particles,
preventing infections from spreading.

19
Q

What is the lymph fluid?

A

Clear fluid carrying white blood cells, carrying immune cells like lymphocytes (made in the bone marrow) to different parts of the body
Flows through the Lymph Vessels
Clears out waste and pathogens
Transports nutrients, waste, and immune cells to and from tissues.

20
Q

What is the thymus?

A

Located in the chest above the heart; crucial for immune development in childhood.
Site of T-cell maturation, helping develop the body’s ability to fight infections.

21
Q

What is the spleen?

A

Largest lymphatic organ, located on the left side of the abdomen.
Filters blood to remove old or damaged red blood cells and helps fight certain bacteria.

22
Q

What is innate immunity?

A

Non-specific: Responds to all pathogens in the same way.
Immediate Response: Acts quickly upon infection.
Physical Barriers: Skin, mucous membranes
Cells: Phagocytes and natural killer cells.
Chemical Defenses: Enzymes in saliva, stomach acid.

23
Q

What is the adaptive immunity?

A

Specific: Targets specific pathogens.
Memory: Remembers past infections, allowing for a faster response upon re-exposure.
Humoral Immunity: Involves B cells that produce antibodies.
Cellular Immunity: Involves T cells that destroy infected cells or help other immune cells.

24
Q

What are the parts of adaptive immunity?

A

passive, active immunity.

25
Q

What is passive immunity?

A

Developed through exposure to a pathogen or through vaccination. Lasts a long time, sometimes a lifetime.

26
Q

What is active immunity?

A

Acquired by receiving antibodies from another source (e.g., maternal antibodies). Provides short-term protection.

27
Q

What are the pros and cons of artificial immunity?

A

pros:
Disease Prevention
Herd Immunity
Long-lasting Protection
Cost-effective
Eradication of Diseases
Safe and Controlled

cons:
Adverse Reactions (Side Effects)
Not 100% Effective
Need for Booster Shots
Accessibility
Public Hesitancy
Cold Chain Requirement

28
Q

What are common ways for diseases to get spread?

A

Direct Contact: Involves physical contact with an infected person, such as touching or sexual contact.

Indirect Contact: Occurs through surfaces or objects contaminated by an infected person, such as doorknobs or utensils.

Airborne Transmission: Involves pathogens that remain suspended in the air over long distances and time, like those from coughing or sneezing.

Vector-Borne Transmission: Involves transmission through vectors, like mosquitoes, which carry the disease from one host to another.

Bloodborne Transmission: Involves the transfer of pathogens through blood, commonly seen in diseases like HIV or hepatitis.

29
Q

What are some diseases related to the immune system?

A

autoimmune disease, immunodeficiency disease, cancerous cells, allergic diseases, inflammatory diseases.

30
Q

What is the autoimmune disease?

A

The immune system mistakenly attacks the body’s own cells. Examples include:
Rheumatoid Arthritis
Lupus (Systemic Lupus Erythematosus)
Multiple Sclerosis
Type 1 Diabetes

31
Q

What is the inflammatory disease?

A

Chronic inflammation due to immune system dysregulation. Examples include:
Inflammatory Bowel Disease (Crohn’s Disease and Ulcerative Colitis)
Psoriasis

32
Q

What is the allergic disease?

A

The immune system overreacts to harmless substances. Examples include:
Allergic Rhinitis
Asthma
Food Allergies
Eczema

33
Q

What is the cancerous cell disease?

A

Where immune cells become cancerous, Examples Include:
Lymphomas
Leukemias

34
Q

What is the immunodeficiency disease?

A

The immune system is underactive or absent. Examples include:
Primary Immunodeficiency Diseases (e.g., Severe Combined Immunodeficiency)
Acquired Immunodeficiency Syndrome (AIDS)

35
Q

What are some ways to prevent immune diseases?

A
  1. BALANCED DIET: EAT PLENTY OF FRUITS, VEGETABLES, WHOLE GRAINS, AND LEAN PROTEINS.
  2. REGULAR EXERCISE: AIM FOR AT LEAST 150 MINUTES OF MODERATE AEROBIC ACTIVITY EACH WEEK
  3. ADEQUATE SLEEP: AIM FOR 7-9 HOURS OF QUALITY SLEEP PER NIGHT, AS SLEEP IS CRUCIAL FOR IMMUNE FUNCTION.
  4. HYDRATION: DRINK PLENTY OF WATER TO HELP YOUR BODY FUNCTION OPTIMALLY
  5. STRESS MANAGEMENT: PRACTICE RELAXATION TECHNIQUES LIKE MEDITATION, YOGA, OR DEEP BREATHING TO REDUCE STRESS.