Homeostasis Flashcards
What is homeostasis?
Ability to maintain a relatively constant internal environment
Name 3 components of the internal environment that are regulated.
- temperature
- volume
- composition
Homeostasis requires…
organ systems integration
Disruption of homeostasis is …
the basis for disease and death
How does fever alter set point?
- rise in core body temperature
- accompanies infection
- White blood cells induce fever by chemical secretion
- Body temperature set point increases
- Fever enhances immune responses
Name another process that alters set point.
exercise
What is negative feedback?
- If a regulated variable decreases, the system responds to make it increase, and vice versa
- Self-correcting
Define regulated variable.
that aspect which is maintained
Give examples of regulated variables.
- blood glucose
- blood pH
- plasma ion concentrations
- hormones
Define set point.
expected value of a regulated variable
Define error signal.
Difference between the value of the set point and the value of the regulated variable
Name 4 structures enabling homeostasis.
- receptors
- integrating centres
- effectors
- signals
What do receptors do? Give examples.
- sensors that detect stimuli
- thermoreceptors
- chemoreceptors
- baroreceptors
What do integrating centres do? Give examples.
- sets up a appropriate response
- medulla oblongata
- hypothalamus (ie. temperature)
What do effectors do? Give examples.
- responsible for body responses
- muscles (smooth, striated, cardiac)
- glands
What do signals do? Give examples.
- Allow components to communicate
- Input signal is from a receptor to an integrating centre
- Output signal is from an integrating center to an effector
- Signals are chemical messages or are sent via neurons
Describe a negative feedback loop.
- set point (normal blood glucose)
- change in regulated variable (increased blood glucose)
- integrating centre (beta cells of pancreas): increased signals to effectors
- effectors (cells throughout the body): response/decreased blood glucose
- negative feedback
- change in regulated variable (increased blood glucose)
- set point (normal blood glucose)