HIV/AIDS Flashcards
do a lot of people of HIV/AIDS
yes.
what are some risk factors for HIV
- health care workers
- geriatric population (55-64)
- drug abuse (with needles)
- mother to baby
what are some sexual practices that can lead to HIV
- sexual exposure with someone
- oral sex
what is HIV
- viruses are intracellular parasites
- infectious disease
- affects immune system
- belongs to a group of retroviruses (carries its own little genetic material in RNA)
HIV infects:
- target cell is CD4 T cells (this causes the loss of immune function)
- mnocytes
- dendritic cells and microganglia (causes dementia)
there are two stages of HIV, what are they
- early (when the virus first takes over)
- late (AIDS)
how does HIV infect
it attaches to the target cell membrane (T cell) then goes around and infects other cells and fucks everything up
name some HIV diagnostics
- ELISA
- antigen/antibody differentiation tests
- CD4 + T cell
- viral load testing
describe ELISA
- enzyme immunoassay
- positive results mean antibodies detected
- takes the antibodies like 2 weeks to show up
describe antigen/antibody differentiation tests
- detects HIV virus
- used to confirm ELISA
describe CD4 + T cell
- count measures overall immune function
- used for HIV staging
describe viral load testing
- measures HIV RNA in blood
- help measure response to treatment
- the lower the viral load, the longer survival time
name and describe the stages of advancement of HIV
- stage 0: early infection, first two weeks, period when it first happens, antibodies are being made
- stage 1: >500 CD4 + T
- stage 2: 200-499 CD4 + T
- stage 3: <200 CD4+ T
what are some early symptoms of HIV
- disappear in a week to month
- highly infectious during this period
- fever, fatigue, lymphadenopathy
- high viral load
what are some later symptoms of HIV
- lack of energy
- weight loss
- fevers/sweats
- N/V
- headache
- truncal rash
- ulcers of mouth, genitals, or both
- thrush
how many positive tests do you need to diagnose HIV
two
what is AIDS
- most advanced stages of HIB infection
- all HIV infected ppl with < 200 CD4+ T cells and with one or more AIDS defining illnesses
name some AIDS defining illnesses
- opportunistic infections
- cancers
- HIV encephalopathy (AIDS dementia)
- HIV wasting syndrome (severeweight loss, N/V, diarrhea lasting longer than 30 days)
name a few common oppportunistic infections associated with AIDS
- pneumocystis pneumonia: fever, cough, hypoxia
- mycobacterium avium complex: night sweats, weight loss, diarrhea
- tuberculosis: hemoptysis, night sweats, weight loss
- candidiasis: white oral lesions, coated tongue
whats the prevention for HIV/AIDS
- PrEP (pre exposure prophylaxis)
- medicines can work to keep the virus from establishing a permanent infection
- can help limit spread of virus to others
- tenofovir and emtricitabine
describe treatment of HIV/AIDS
- HIV mutates rapidly and causes resistance to antiretroviral drugs
- use combo therapy (ART)
- ART drugs play a key role in interrupting the HIB process: inhibits, reduces, and halts
what are some adverse effects to all HIV/AIDS treatment regimens
- hepatotoxicity
- nephrotoxicity
- osteopenia
- increased risk of CVD and MI
whats the prognosis of HIV/AIDS
illness varies from person to person
- long term nonprogressor: immune system takes control and stay in HIV
- long term survivor: stay in AIDS
increase mortality/morbidity
- lower SES
- lack of access
- limited AIDS experience
- physician with little experience in AIDS care
what are some nursing interventions for HIV/AIDS
- prevent progression
- assess for clinical manifestations
- increase caloric intake and fluids
- maintain comfort and safety
- prevent fatigue
- patient/fam education on preventing further infections
true or false
pts may have false negative HIV antibody testing immediately after exposure
true
it takes about two weeks for the body to make antibodies against HIV so antibody testing may show negative results until bdy has made them
which lab value do we monitor in evaluating the progression of HIV?
CD4
the lower the count, the more advanced the HIV has become