disorders of the kidney Flashcards
describe AKI
- sudden onset/reversible
- causes can be pre-renal, intra renal, post renal, or nephrotoxins
- symptoms may vary
- goal to keep patients alive until renal lesion heals
- 40-60% mortality
what are some pre renal causes of AKI
low BP
what are some intra renal causes of AKI
kidney infection or dye damage
what are some post renal causes of AKI
kindey stone or tumor blocking urine leaving the kidney
describe CKD
- slow progression/irreversible
- causes include diabetes and hypertension (both cause repetitive damage to glomerulus
- symptoms vary
- goal to slow or prevent progression with dialysis or transplant
- 100% mortality wihtout treatment
define CKD
kidney damage or decrease in GFR > 3months
insidious, progressive loss of renal function
what are soem risk factors for CKD
- diabetes (primary cause)
- hypertension (second leading cause)
- glomerulonephritis/pyelonephritis
- polycystic kidney
- heredity/congenital
- renal cancers
what are some signs and symptoms of CKD
- elevated serum Cr and BUN
- electrolyte abnormalities
- anemia
- metabolic acidosis
- fluid retention
- heart failure
can vary from mild to severe, most arent noticed until severe
what is the initial goal of CKD
prevent or slow progression of failure
treat underlying causes
what are some interventions for CKD
- renal diet
- control HTN
- control glucose levels
- assess meds
what is the goal of the renal diet
to decrease production of metabolic watses and regulate electrolytes
whats included in the renal diet
- low protein
- low potassium
- low sodium
- low phosphorus
- fluid restriction (late stages) may be 1000-1500ml/day
what are some food sources that are high in potassium
- salt substitutes
- potatoes (unless dialyzed)
- oranges and OJ
- bananas
- prune juice
- tomato
- dried beans and lentils
- nuts, chocolate, coconut
what are some food sources that are high in phosphorus
- milk
- milk products
- fish
- chicken and beef liver
- legumes
- whole grain breads and cereal
- peanut butter
- colas
what are some nephrotoxic meds
- diuretics
- ace inhibitors
- aminoglycosides
- metformin
- nsaids
describe the first stage of CKD
- kidney damage with normal or increased GFR
- treatment of underlying condition and comorbidities
- no symptoms
describe the second stage of CKD
- mild
- estimate the rate of progression
- no symptoms
describe the third stage of CKD
- moderate
- evaluate and treat complications
describe the fourth stage of CKD
- severe
- prepare for renal replacment therapy
describe the fifth stage of CKD
- kindey failure, end stage
- dialysis or transplantation
what are the multisystem effects of ESKD
- neurologic: toxins and electrolytes buiding up -> concern for seizures and confusion
- inetgumentary: easy bleeding or bruising, thin hair, uremic frost, pruritis
- CV: fatal K+ levels, edema
- pulmonary: SOB, crackles
- GI: metallic taste in mouth, anorexia
- hematologic: anemia
- MSK: increased risk for bone fractures, osteoporosis, bone pain (decreased Ca)
what are some fluid/electrolyte imbalances that occur with ESKD
- sodium retention
- potassium retention
- acidosis
- increased phosphorus and decreased calcium
what is uremic frost
when the body tries to sweat urea out, causes salty coating on skin
true or false
intrarenal failure may be caused by meds such as metoprolol
false
metprolol is not nephrotoxic