Histology - Male Reproductive System

Question 1

seminiferous, open, euchromatic -nucleolus

Answer 1

Sustentacular cell

Question 1

“checkerboard” nucleus, middle layer

Answer 1

Primary spermatocyte

Question 2

low back pain, urethral discharge, fever. Expressed prostatic secretions (EPS) culture

Answer 2

Prostatitis

Question 3

Testis Septa

Answer 3

CT that divides testis into lobules

Question 3

the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.

Answer 3

Seminiferous tubules

Question 3

tumors that arise from sustentacular cells or interstitial cells

Answer 3

Sex cord-stromal tumors

Question 4

Testis dense CT capsule

Answer 4

Tunica albuginea

Question 6

inflammatory response within IT of testis (e.g., viral mumps in adults, syphilis)

Answer 6

Orchitis - scarring may cause infertility, T production often not significantly affected

Question 7

produce sperm

Answer 7

spermatogenic cells

Question 8

Semiferous epithelium, 3 layers

Answer 8

Seminiferous (germinal) epithelium, basement membrane, tunica propria

Question 9

nuclei along the BM

Answer 9

Spermatogonia

Question 9

Found from transitional zone. Associated with DHT, stromal cells convert T to DHT, dysuria, secondary UTIs (urine retention)

Answer 9

Benign prostatic hyperplasia (BPH)

Question 10

have the appearance of a mucus-secreting gland. lubricates the urethra with pre-seminal mucus

Answer 10

bulbourethral glands

Question 12

produce testosterone (T)

Answer 12

interstitial cells (of Leydig)

Question 13

defining histologyical feature of prostate gland

Answer 13

prostatic concretions

Question 14

testis are responsible for…

Answer 14

spermatogenesis: exocrine (holocrine) secretion of sperm AND steroidogenesis: endocrine secretion of testosterone

Question 15

yield primary spermatocytes by mitosis…

Answer 15

spermatogonia

Question 16

disruption of the B-T barrier, antisperm antibodies (ASA)

Answer 16

Immune infertility

Question 17

The seminiferous tubules are formed from…

Answer 17

primitive sex cords. It is the medullary cords which develop into the seminiferous tubules and the cortical cords regress. The cords were formed from the gonadal ridge.

Question 18

Interstitial tissue (IT) loose connective tissue stroma that contains…

Answer 18

fenestrated capillaries, interstitial cells (of Leydig): produce testosterone (T)

Question 20

Tumors that arise from spermatogenic cells;

Answer 20

Germ cell tumors, most common (95%).

Question 21

regulates glandular epithelium growth and metabolism

Answer 21

Prostatic acid phosphatase (PAP)

Question 22

small, dark nucleus, near lumen

Answer 22

Spermatid

Question 23

produce ABP, MIS, inhibin, fructose-rich fluid

Answer 23

sustentacular (Sertoli) cells

Question 24

days until the effects of an antispermatogenic agent are fully observable

Answer 24

86 days, 74 in testis, 12+ to mature in epididymis

Question 25

Formed by tight junctions between sustentacular cells

Answer 25

Blood-testis barrier. Sequesters testosterone in luminal compartment -necessary for spermatogenesis. Gap junctions coordinate activity.

Question 26

Seminiferous tubules epithelium

Answer 26

sustentacular or Sertoli cells, which are tall, columnar type cells that line the tubule.

Question 27

primary spermatocyte divides meiotically into …

Answer 27

two secondary spermatocytes. Each secondary spermatocyte then completes meiosis as it divides into two spermatids which developninto mature spermatozoa (sperm cells).

Question 29

Seminiferous (germinal) epithelium:

Answer 29

spermatogenic cells and sustentacular cells

Question 30

most resistant to BPH, prostatitis, & cancer

Answer 30

Central zone