Histology - GI System Flashcards

1
Q

Replace all cell types

A

Stem cells (in isthmus)

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1
Q

parts of GI tract with submucosal glands

A

duodenum, esophagus

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2
Q

Stomach - ELSMS/A

A

E: simple columnar LP: fundic, cardiac, pyloric glands SM: rugae ME: inner oblique, middle circular, outer longitundinal. S/A: serosa

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2
Q

Small Intestine - ELSMS/A

A

E: simple columnae LP: vili, intestinal glands, Peyer’s patches (ileum). SM: circular folds, Brunner’s glands. ME: inner circular, outer longitunindal. S/A: serosa (except duodenum)

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3
Q

apical, small intestine. Antimicrobial secretions that regulate gut flora.

A

Paneth cells

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4
Q

HCl: lowers pH. Intrinsic factor: B12 absorption

A

Parietal cells

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5
Q

Smooth Muscle Sphincter Layer

A

Muscularis Externa

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6
Q

lymphatic capillaries, uptake chylomicrons (modified triglycerides)

A

Lacteals

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6
Q

Transition from simple columnar to stratified columnar to stratified squamous non keratinized

A

Rectoanal junction

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7
Q

Pepsinogen: converted to pepsin by low pH, digests protein

A

Chief cells

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7
Q

Esophagus - ELSMS/A

A

E: Stratified squamous non-keratinized LP: esophageal cardiac glands (lower) SM: esophageal glands ME: skeletal (upper) -> sk & sm (middle) -> smooth (lower) S/A: Adventitia

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9
Q

Secrete hormones like gastrin, CCK, secretin. Regulate gastric, intestinal, pancreatic, gallbladder activity -G cells, I cells, S cells, etc.

A

Enteroendocrine cells

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10
Q

antigen transport cells, phagocytizes antigen & transports it to lamina propria

A

M cells

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11
Q

Soluble mucus: lubrication

A

Mucous neck cells

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11
Q

Large Intesting - ELSMS/A

A

E: simple columnar. LP: intestinal glands. SM: - ME: inner circular, outer longintudinal (teniae coli). S/A: serosa in transverse and sigmoid. Adventitia in the rest.

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12
Q

submucosal glands

A

Esophageal glands, Brunner’s Glands (duodenum)

14
Q

Lacteals, fenestrated capillaries, smooth muscle, GALT

A

Villus lamina propria components

16
Q

cells found in the follicle-associated epithelium of the Peyer’s patch that transportantigens from the gut lumen to immune cells across the epithelial barrier, and thus are important in stimulating mucosal immunity.

A

M cells (or microfold cells) are

17
Q

permanent infolds of the lamina propria

A

Intestinal glands

19
Q

Insoluble mucus: barrier

A

Surface mucous cells

20
Q

Gut mucosal immunology

A
  1. M cells phagocytize antigen and transport ot LP. 2. Immune cells in GALT activate plasma cells. 3. Plasma cells secrete antibodies that are transported to the lumen.
21
Q

outer layer of adventitia

A

distal duodenum, esophagus, ascending and descending colon, rectum

22
Q

goblet cells secrete mucus for lubrication & protection

A

Intestinal glands

23
Q

cytoplasmic folds on enterocytes

A

Microvilli

24
LARGE INTESTINE functions
absorbs electrolytes & water, eliminates waste
25
Enterocytes, Goblet Cells
Villus epithelium components
27
Fundic Glands
surface mucous cels, stem cells, mucous neck cells, parietal cells, chief cells, enteroendocrine cells
28
Stratified squamous non-keratinized to statified squamous keratinized at anus. Internal anal sphincter is smooth muscle while external anal canal is skeletal muscle.
Anal canal
29
permanent outfolds of the lamina propria
Villi
30
permanent folds of submucosa
Circular folds (plicae circulares)
31
LARGE INTESTINE unique features.
Simple columnar epithelium, intestinal glands in LP, teniae coli in outerlongitudinal layer