Hepatitis Flashcards
hepatitis
Inflammation of the liver
causes
Viruses, alcohol, autoimmune disease
Hepatitis A
Caused by the hepatitis A virus– transmitted
through ingestion of fecal matter containing the
virus
Hepatitis B
Caused by the hepatitis B virus – transmitted
through contact with infected body fluids (blood,
semen). Can also be transmitted from a mom to
baby during childbirth
Hepatitis C
caused by the hepatitis C virus – transmitted
through blood contact from shared needles or
improper sterilization of healthcare tools
Hepatitis D
Caused by the hepatitis D virus– cannot cause
infection on its own, only develops in people
already infected with the hepatitis B virus
Hepatitis E
Caused by the hepatitis E virus– transmitted
through the consumption of contaminated water
or food.
chronic
ssRNA types
Types A, C, E, D
ssRNA steps 1 and 2
1.Virus enters through endocytosis and releases RNA
- RNA goes to the host cell ribosome to synthesize proteins
-makes capsomeres, antigens, and
RNA polymerase
ssRNA steps 3 and 4
- Proteins go to the golgi and are packaged in vesicles
- RNA polymerase increases RNA production to combine with proteins to form
viruses
dsRNA type
type B
dsDNA step 1
Virus enters hepatocyte and releases DNA into nucleus
dsDNA step 2-4
- DNA can use cell RNA polymerase to make viral RNA
- RNA can make mRNA to make more proteins in ribosome
- RNA can use reverse transcriptase enzyme to make DNA
dsDNA steps 5-6
- DNA combines with proteins in vesicles to form virus
- Viral DNA uses host DNA polymerase to keep self-replicating
Chronic hepatitis
-Down regulate T cell response
-surface antigen wins over IgG
antibodies
-dsDNA self-replicating
