Diabetes Flashcards

1
Q

Diabetes

A

Disease in which the bodys ability to produce or respond to hormone insulin is
impaired and results in an abnormal metabolism of carbs

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2
Q

type 1 diabetes

A

Immune system mistakenly treats the beta cells in your pancreas that create insulin as foreign invaders and destroys them,
○ When enough are destroyed pancreas cannot make insulin or makes so little
of it

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3
Q

result of type 1 lack of insulin

A

Glucose builds up in our blood stream because without insulin blood glucose cannot enter the cells which causes high blood glucose or hyperglycemia

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4
Q

type 1 is an..

A

autoimmune disorder with an attack on beta cells that secrete insulin normally

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5
Q

type one environmental infections

A

Coxsackie virus, enteroviruses, cytomegalovirus, rubella,
influenza B, mumps virus, SARS-CoV-2 (covid 19)

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6
Q

second cause of type 1

A

Presence of circulating pancreatic islet autoantibodies

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7
Q

inflammatory cytokines

A

TNFα IFNγ and IL-1β

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8
Q

type 2 diabetes

A
  • Pancreas does not produce enough insulin
  • Cells respond poorly to insulin and take in less sugar
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9
Q

type 2 process step 1

A

Cells in muscle, fat and the liver become resistant to insulin, because of this the cells do not take in enough sugar

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10
Q

type 2 process step 2

A

Pancreas doesn’t make enough insulin to keep blood sugar levels within a healthy rang

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11
Q

Insulin resistance

A

A lot of blood sugar enters bloodstream→ pancreas pumps high levels of insulin→ cells stop responding to insulin→ blood sugar stays high which causes pancreas to release more insulin → as result pancreas cannot keep up and blood sugars keep increasing

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