Epilepsy Flashcards

1
Q

epilepsy

A

Neurological disorder that causes multiple unprovoked reoccurring seizures
that are usually caused by triggers

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2
Q

epileptic episode needs…

A

2 or more seizures need to occur in order for it to be an epileptic episode

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2
Q

Focal

A

single hemisphere/part if
brain is involved

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2
Q

4 types of epilepsy

A

1) Focal
2) Generalized
3) Generalized AND Focal
4) Unknown

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3
Q

Focal types

A

-Focal aware (atonic)
-Focal impaired (Partial)
- Focal motor (simple-partial)
- Focal non-motor

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4
Q

Generalized

A

Both hemispheres of brain are
involved**

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5
Q

Generalized types

A

1) Generalized tonic-clonic
(motor) (”grand mal”)
2) Generalized Absence
(non-motor) (”petit mal”)

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6
Q

Inhibitory pathway

A

1)GABA is released
2)Acts on GABA-R which causes channels to open
3)Allows Cl- to enter
4)Causes hyperpolarization and Inhibits activity of AP’s

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7
Q

Excitatory pathway

A

1)Glutamate is released
2)Acts on NMDA and AMPA receptors
3)Allows NA+ and Ca+ to enter
4)Causes depolarization and AP’s

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8
Q

GABA-R receptors

A

dysfunctional

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9
Q

AMPA and NDMA receptors

A

general seizure

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10
Q

NMDA

A

brain’s primary NT- allows for Ca permeability

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11
Q

AMPA

A

mediate fast synaptic transmission within the CNS; allows for Na+ permeability

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12
Q

Glutamate activity

A

high during epileptic events

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