Glucosamine Flashcards
Glucosamine Basic building block of
.
Glucosamine - Supplements
.
Glucosamine Often combined with
.
Retain H
2
O in the cartilage →
.
Glucosamine – Potential Health Benefits
.
Insufficient evidence to use glucosamine for:
.
Osteoarthritis
/
Osteoarthritis Symptoms
.
Treatment of Osteoarthritis
.
Precursor to chemicals that are involved in building
.
increase the cartilage and fluid surrounding
joints or help prevent breakdown of these substances, or maybe both.
.
Glucosamine – How Does it Work?
.
synergistic effect in treating knee
osteoarthritis
.
Glucosamine - Precautions
.
Glucosamine - Drug Interactions
.
Glucosamine Legal Status
.
Stimulate synthesis of proteoglycans and
glycosaminoglycans .
L
Chondroitin Sulfate
.
symptomatic benefit is minimal
.
Some studies suggest that taking recommended dose over a long time →
.
Long Term Evaluation of Glucosamine Sulfate (Large LEGS)
.
weeks to see improvement in symptoms.
.
Be a helpful option for people who can’t take nonsteroidal anti-inflammatory
drugs (NSAIDs).
.
glycosaminoglycans
.
proteoglycans
.
Amino sugar synthesized from glucose and
glutamine.
.
—————> support joint, slow disease
progression.
.
Rheumatoid arthritis
.
Recovery after surgery
.
Temporomandibular disorder
.
glaucoma
.
Interstitial cystitis
.
Grating sensation:
.
Loss of flexibility
.
Bone spurs:
.
Precursor to chemicals that are involved in building tendons, ligaments, cartilage,
and synovial fluid that surrounds joints.
.
is found endogenously in the body
.
glucosamine supplements may either increase the cartilage and fluid surrounding
joints or help prevent breakdown of these substances, or maybe both.
.
——-May be needed by the body to produce cartilage
.
Stimulates biosynthesis of proteoglycans.
.
collagenase
.
phospholipase
.
It is recommended to stop glucosamine supplements 2 weeks before elective
surgery (might affect glucose levels)
.
Tylenol
.
Coumadin
.
Jantoven
.
chain of alternating
sugars (N-acetylgalactosamine) and glucuronic acid
.
Supplements derived from bovine or shark
.
Some studies suggest that taking recommended dose over a long time →
.
The pharmacological effect/ improvement in symptoms could be due to
;
Studies on chondroitin alone showed that
.
The earlier the use of————, the better
.
may take 2-4 weeks to see improvement in symptoms.
.
Most clinical trials were conducted using ————which might be
helpful for osteoarthritis.
.