Collagen Peptides Flashcards
is the most ubiquitous protein in the
human body.
.
the oldest
protein identified so far,
.
fibrous protein that make up the connective
tissues in the human body, particularly, skin, joints,
and bones
.
Chemical Structure and Composition
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Collagen molecules consist of ……… (alpha-chain), which wrap
around each other in a triple-helical
structure held together by …..between the chain.
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• It is mainly comprised of three amino
acids …..
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This allows the
three chains to combine into a ….l.shape
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As a result, all collagens have a sequence that may be written as (Gly-X-Y)*n, where X and Y are commonly ..... (Pro) and ..... (Hyp), correspondingly.
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Physical properties
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Low viscosity in aqueous solutions.
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Neutral odor.
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Colorless
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Transparent
.
stabile
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Water soluble.
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The stability is due to it’s stereoelectric effect.
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affect on molecular geometry, reactivity, or
physical properties due to the interaction between atomic and/or
molecular orbitals.
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Collagen can be obtained from the diet by consuming:
/
helps the development of the organs; wound and
tissue healing. Collagen helps in bone and blood
vessel reparation
.
Sources for extraction
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The most common animal sources of collagen are
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It has been reported that has no risk of transmitting diseases, it has been
considered as GRAS (Generally recognized as safe) by the FDA.
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Mechanism of action
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can be used as an ingredient for functional food supplements because
they present antioxidant and antimicrobial activity.
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Hydrolyzed collagen to act as an …..to produce more stable products reacting
with free radicals.
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In the dermis, collagen peptides have ….. that provide building blocks for the
formation of collagen and elastin fibers.
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act as ligands that bind to receptors present on the fibroblasts’
membrane and stimulate the production of new collagen, elastin, and hyalronic acid.
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Health benefits
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increase the bone mineral density (BMD) in postmenopausal women.
_
preventing osteoporosis. But more studies should be conducted.
.
improve wound healing.
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Health claims
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improving memory, claimed by in vivo studies.
;
aid in the maintenance of a healthy cardiovascular system.
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Collagen role in beauty, dermatology, and anti-aging effects
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commercialized as a tool in wrinkle reduction, skin-rejuvenation, skin-aging
reversal, and skin plumping. In contrast, it hasn’t been clinically proven as there are no strong evidence to back this claim.
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Therefore, the studies suggest that the use of oral collagen supplements may benefit the skin to some
extent. However, many factors need to be taken into consideration first.
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Safety
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the use of fish hydrolyzed collagen is associated with episodes of anaphylaxis
characterized by
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- swine flu and bovine spongiform encephalopathy.
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