Garcinia Cambogia Flashcards
Physical Properties & Source
.
tropical fruit that grows on a
small to medium tree in countries of Southeast Asia.
.
The fruit of the tree is small, green to yellow in color
with six to eight grooves, and it looks like a small
pumpkin.
.
The rind of the fruit has a sour taste and used as a
flavoring agent.
.
The supplement extract is taken from the skin after it
has been dehydrated.
.
Composition & Chemical structure
.
It contains a large amount of
……which
is the main active ingredient
responsible for its effect.
.
Proven Uses
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Weight loss
.
Hyperlipdiema
L
reduction in LDL and increase in HDL.
.
Mechanism of Action
.
competitive inhibitor of the enzyme ATP citrate lyase.
.
This enzyme is a key enzyme in the synthesis of fatty acids, cholesterol, and
triglycerides.
.
inhibiting the enzyme will inhibit the synthesis of these components.
.
reduces food intake by regulation of serotonin level.
.
Anti inflammatory activity
L
Anti oxidant activity
K
Hepatoprotective activity
L
Anti-cancer activity
O
Anti-ulcer activity
K
anti-inflammatory activity in rats with induced colitis.
L
An in vitro assessment was done by extracting the dried fruit rind in four
solvents (hexane, ethyl acetate, ethanol and hydro-alcoholic extracts).
.
tumoricidal effect against cancer cells.
.
damage by decreasing the volume and acidity of gastric
juice.
L
According to the manufacturer, the products contain at least 60% ……..
.
They recommend one capsule 30 minutes before meal three times daily.
L
they recommend one cup 30 minutes prior to a meal
.
The powder they recommend to mix one scoop with 8 oz of water or juice.
L
Side Effects
.
some cases reported acute hepatitis as well as mania and
serotonin toxicity.
.
Contraindications
.
Should not be used in patients taking medications for diabetes
.
