CREATINE Flashcards

1
Q

endogenous amino acid derivative found largely in muscle cells and synthesized by us

A

L

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2
Q

nitrogen-containing ….. derivative with ….. and ….. groups attached Due to intramolecular cyclisation to creatinine

A

.

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3
Q

creatine is not ….. in aqueous solution.

A

L

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4
Q

is formed when a portion of total creatine binds to

phosphate in the muscles.

A

K

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5
Q
..... catalyzes the process, which
produces phosphocreatine (PCr).
A

O

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6
Q

Phosphocreatine binds to adenosine
diphosphate and converts it to ATP (adenosine triphosphate), a crucial cellular
energy source for short-term …… demands before oxidative phosphorylation.

A

.

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7
Q

Sources

A

H

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8
Q

made in our body 1 gram per day by the liver pancreas and the kidneys

A

K

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9
Q

Muscle mass and strength.

A

K

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10
Q

Increase Lean body mass

A

H

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11
Q

Increase the endurance and strength

A

G

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12
Q

It shows a excellent effect for the people in rehabilitation programs

A

K

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13
Q

If its taken by postmenopoasul women it increase the strength and bone density

A

J

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14
Q

Lows weight and maintain muscle

A

G

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15
Q

retain muscle mass

A

K

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16
Q

stimulate fat reduction

A

O

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17
Q

control adult-onset obesity.

A

I

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18
Q

Diabetes

A

N

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19
Q

reduce GLUT-4 transporter reductions during

immobility while also raising GLUT4- after atrophy restoration

A

J

20
Q

control blood glucose and reduce HBA1c and increase

insulin sensitivity

A

H

21
Q

Treatment for some conditions

A

J

22
Q

improve both muscular dystrophies and idiopathic inflammatory
myopathy if the patient took creatine supplement

A

J

23
Q

Skin

A

R

24
Q

Antioxidants

A

F

25
Q

Anti wrinkles

A

F

26
Q

Help in hydration of the skin

A

F

27
Q

Cognitive Function

A

N

28
Q

raise PCr content in the brain and hence improve

brain function

A

J

29
Q

boosted oxygen consumption in the brain and decreased mental tiredness in those who did
repetitive mathematical computations.

A

J

30
Q

enhanced working memory and

processing speed

A

;

31
Q

Improve the sleep

A

E

32
Q

Heart diseases

A

H

33
Q

can protect the heart form ischemic attacks

A

O

34
Q

Decrease incidence of arrhythmia

A

K

35
Q

Improve myocardial function

A

L

36
Q

Showed some benefit in heart failure patient

A

O

37
Q

Immune

A

L

38
Q

decreasing pro inflammatory cytokines

A

O

39
Q

reducing pulmonary and systemic consequences of lung ischemia

A

L

40
Q

Dosage forms and recommended doses

A

L

41
Q

Dosage regimens in clinical trials vary from 2 to 20 g daily and from a week up to 3 years

A

J

42
Q

There is another dosing method the loading method in which the patient take 5 g 4 time a day for
10

A

I

43
Q

Side-effects (adverse drug reactions) and contraindications.

A

I

44
Q

there is a study concluded that creatine may may promote metastasis of some cancers [

A

;

45
Q

should be avoided in renal insufficiency because it might build up in the body.

A

L