Evening primrose oil Flashcards
is a yellow wildflower,
belonging to the family
Onagraceae.
K
It grows in North
and South America
K
that’s why it is called
evening primrose.
J
is famous by its yellow
or gold color with cross-shaped
stigma
I
It can tolerate the dryness.
U
The primrose oil is extracted from
the seeds Oenothera biennis by
cold press, as the seeds are
squeezed at very high pressure
I
It can be extracted also by solvent extraction using hexane as a solvent. A proper antioxidant can be added.
I
The primrose oil contains mainly…
.
Composition
J
palmitic acid,
J
oleic acid,
I
stearic acid.
I
Other minor elements contain alcohol, sterols, and triterpine alcohol.
M
Proven uses
K
Menopausal hot flashes
O
Improving lipid profile
L
Effect on the skin
K
Treatment of rheumatoid
arthritis
M
the most common symptoms experienced by
menopausal women and affect the quality of
life as a result of oestrogen withdrawal.
.
produce prostaglandins
K
reduce the hormonal changes related to
menopause.
K
did not
have significant effect on serum
total cholesterol and LDL level.
K
decreased the level of triglycerides
`i
strengthen the epidermal barrier,
O
prevent the excessive loss of water
J
regenerates skin,
and improves smoothness
J
leads to its
replacement by oleic acid. This will
affect the protective properties of
the epidermis layer.
K
improvement in skin regarding
skin moisture and flexibility
,
reducing joints pain in rheumatoid
arthritis patients.
H
that it reduced the use of NSAIDs
during the trial period.
I
Unproven uses
U
diabetic neuropathy
U
I
asthma
K
cancer
O
atopic dermatitis
K
Mechanism of action
K
rich
in polyunsaturated omega-6 essential
fatty acids including linoleic acid and
gamma-linolenic acid.
K
precursors of anti-inflammatory
eicosanoids (e.g., prostaglandins,
cytokines, cytokine mediators)
K
suppress inflammatory
responses by directly acting on
inflammatory cells.
17
K
Side effects
J
lipoid pneumonia
K
headache
K
nausea and GI cramps
J
reduce the threshold of seizure
M
has anticoagulant effect, so can interact with anticoagulant drugs and
lead to bleeding
K
In pregnancy and lactation, the use of primrose oil is unsupported, so
better to be avoided.
K
Dosage form and doses
,