GI Flashcards
What two groups of organs make up the digestive system
Gastrointestinal tract (alimentary)
Accessory digestive organs
The gastrointestinal tract extends from the __________ to the _________
Mouth to the anus
What anatomy is considered the GI tract
Mouth
Pharynx
Esophagus
Stomach
Small intestine
Large intestine
What are the accessory digestive organs
Teeth
tongue
salivary gland
liver
gallbladder
Pancreas
What is the function of accessory digestive organs
Aid in digestion
What are the three regions of the abdomen
Intrathoracic
True abdomen
Retroperitoneal
What defines an organ as intrathoracic
Enclosed by the lower ribs and immediately distal to the diaphragm
Intrathoracic organs
Liver
Gallbladder
Spleen
Stomach
Transverse
What is contained in the true abdomen
Large and small intestines, portion of the liver, and the bladder
Females: uterus, Fallopian tubes, ovaries
How is retroperitoneal defined
Lies behind the thoracic and true portions, separated by the retroperitoneal membrane
Retroperitoneal organs
Kidneys
Urters
Pancreas
Posterior duodenum
Ascending and descending colon
Inferior vena cava
What are the six basic functions of digestion
Ingestion
Secretion
Mixing and propulsion
Digestion
Absorption
Defecation
What is ingestion
Taking in food and liquid through the mouth
What is secretion
Cells lining the GI tract produce water, acid, buffers and enzymes to aid digestion
What is Mixing and propulsion
Continuous contraction and relaxation moving food along the tract.
What is digestion
Mechanical and chemical process that breaks down food
What is absorption
Small molecules produced in digestion move into spaces to be used by cells
What is defecation
Elimination of materials not absorbed by our body
What are the layers of the GI tract
Mucosa
Submucosa
Muscularis
Serosa
Mucosa in the GI tract is the ________
Innermost lining in direct contact with the substances passing through
What is the submucosa within the GI tract
Areolar connective tissue that connects the mucosa and the muscularis. Contains blood and lymph vessels
What does the muscularis contain within the GI tract
Skeletal and smooth muscles
What are the layers of the serosa
Visceral peritoneum
Parietal peritoneum
What is the visceral peritoneum
Outmost layer around the organs
What is the parietal peritoneum
Lines the walls of the abdominal cavity
Define the greater omentum
Fatty apron that drapes over transverse colon and small intestine
What is mesentery
Binds the small intestine to the posterior abdominal wall
Name the salivary glands
Parotid
Submandibular
Sublingual
What is the function of salivary glands
Dissolve food and begin digestion
Contain lysosomes that kill bacteria
Mucous produced to lubricate food
Amylase begins digestion of starches in mouth
What percentage of saliva is water
99.5% water
0.5% solutes
The tongue is what type of organ
Accessory digestive organ
Define the frenulum
Fold of mucous membrane in the midline underneath tongue that limits posterior movement
What is the function of teeth
Perform mechanical digestion (chewing and breaking down food)
What is the pharynx
Funnel shape tube, located posterior end of oral cavity and comprised of skeletal muscle
Name the branches of the pharynx
Nasopharynx
Oropharynx
Laryngopharynx
Where is the esophagus located
Posterior to the trachea
Where the esophagus begins and ends
Begins at the end of the pharynx
Ends at the superior aspect of the stomach
What are the sphincters of the esophagus
Upper esophageal - skeletal muscle
Lower esophageal - smooth muscle
Define the function of esophagus
Transport food along its path, mixing it with mucous
Phases of swallowing
Voluntary
Pharyngeal
Esophageal
What is voluntary swallowing
Bolus forced into oropharynx from upward movement of tongue against palate
What is pharyngeal swallowing
Breathing is temporarily stopped, soft palate and uvula move up to close of nasopharynx, epiglottis closes off larynx and UES relaxes to allow bolus to move into esophagus
What is esophageal swallowing
Good is pushed through esophagus via peristalsis, LES relaxes and bolus moves to stomach
Describe the stomach
J shaped organ which serves as a mixing chamber for food. Aids in digestion
What is the pH of stomach
2 (acidic, < 7)
The stomach can accommodate up to _____ liters of food
6.4 liters
The stomachs extends from where and ends where
Extends from end of esophagus and ends at the top of the duodenum
Four main regions of stomach
Cardia
Fundus
Body
Pylorus
What are gastric gland cells
Exocrine cells that combine to make gastric juices
What are the 3 types of gastric exocrine cells
Mucous neck cells
Chief cells
Parietal cells
Function of mucous neck cells
Secrete mucous
Function of chief cells
Secrete pepsinogen
Function of parietal cells
Secrete hydrochloride acid and intrinsic factor
What converts Pepsinogen into pepsin
Hydrochloride acid
Why is intrinsic factor needed
Absorption of B12 in small intestines
What is the function of G cells
Secrete gastrin into the bloodstream
What is gastrin
The major hormone regulator of hydrochloride acid secretion
Define Chyme
Thick liquid with pea soup consistency made up up gastric juices and macerated food
What type of functions does the pancreas have
Endocrine and exocrine
Specialized areas within the pancreas are called?
Islets of Langerhans
Islets of langerhans are made up of different cells that make what?
Hormones
The most common cells within the islet of langerhans
Beta cells
Insulin is produced by what cell?
Beta cells
Alpha cells are found where
Islet of langerhans
Alpha cells produce
Glucagon
What role does glucagon play within the body
Prevent blood glucose levels dropping too low
Is the pancreas Retroperitoneal or intra abdominal
Retroperitoneal behind the stomach
Secretions within the pancreas pass through what duct
Pancreatic duct
The hepatopancreatic duct is formed by
The common bile duct and the pancreatic duct
From the hepatopancreatic duct, secretions pass through the
Sphincter of Oddi
What are pancreatic juices
Clear colorless liquid made up of three enzymes
Enzymes in pancreatic juices
Trypsin and chymotrypsin
Pancreatic amylase
Pancreatic lipase
Ribonuclease
Trypsin and chymotrypsin help digest what
Protein, broken down into amino acids, dipeptides and tripeptides
Pancreatic amylase helps digest what
Starch (carbs), absorbed as monosaccharides
Pancreatic lipase breaks down what
Triglyceride (fat), absorbed as monoglycerides and fatty acids
Ribonuclease break down what
Nucleic acid
Second largest organ in the body
Liver
The liver is responsible for what
Carbohydrate metabolism
Lipid metabolism
Protein metabolism
Processing drugs and hormones
Excretion of bilirubin
Storage of vitamins and minerals
Activation of vitamin D
What makes poop brown
Stercobilin
What is the major functional cell of the liver
Hepatocyte
Hepatocytes have what functions
Metabolic
Secretory
Endocrine
Describe the gallbladder
Pear shaped sac that hangs from inferior margin of the liver
Function of the gallbladder
Stores bile
Aids in chemical digestion especially fats
Bile and waste created in the liver are passed into what ducts
Left and right hepatic duct
Bile produced in the gallbladder secreted through what duct
Cystic duct
Muscular valve that controls the passage of contents from the hepatopancreatic duct to the duodenum
Sphincter of Oddi
Segment of GI system that comes after the stomach
Small intestine
Length of the small intestine
Approx 3m (10ft), 6.5 (21ft) cadaver
What are intestinal glands
Contain three types of endocrine cells that secrete hormones into the bloodstream
Types of intestinal gland cells
S cells
CCK cells
K cells
Purpose of S cells
Secrete secretin, stimulates release of pancreatic juices
Purpose of CCK cells
Secrete cholecystokinin, regulates gastric emptying
How do CCK cells stimulate gastric emptying
Stimulates bile and pancreatic juice secretion which causes relaxation of the sphincter of Oddi, and feeling of satiety
Segments of the small intestine
Duodenum
Jejunum
Ileum
Significant landmark of the duodenum
Ligament of Trietz, connects at the duodenal-Jejunal flexure
Ligament of Trietz denotes what
Upper/lower GI bleed
What is the middle section of the small intestine
Jejunum
Primary function of the Jejunum
Absorption of sugars, amino acids, and fatty acids
What attaches to the large intestine at the ileocecal sphincter/valve
Ileum
Function of the ileum
Absorb remaining nutrients, B12, and bile salts
Types of digestion
Mechanical and chemical
What is mechanical digestion
Segmentation and peristalsis
What is chemical digestion
Pancreatic enzymes, bile and intestinal juice
Define absorption
Nutrients are broken down into their simplest form to be absorbed
Last part of the GI tract
Large intestine
Regions of the large intestine
Cecum
Colon
Rectum
Anal canal
The appendix attaches to what
The cecum
Portions of the colon
Ascending/descending
Transverse
Sigmoid
Purpose of the rectum
Connects the sigmoid colon to the anus
What consists of the anal canal
Last 2-3cm of the rectum.
Internal (involuntary) sphincter
External (voluntary) sphincter
Function of the large intestine
Finishes absorption of water, electrolytes and vitamins
Forms and holds feces
What are the phases of digestion
Cephalic
Gastric
Intestinal
What is cephalic digestion
Smell, sight, sound or thought of food stimulates salivary glands and gastric glands
What is gastric digestion
When food enters the stomach, gastrin is released
What is intestinal digestion
Food enters the small intestines, pancreatic juices promote absorption