Gene Tox Flashcards

1
Q

transitions

A

where the change is purine for purine or pyrimidine for pyrimidine

Purines = Adenine and Guanine
Pyrimidine = Cytosine, Thymine, Uracil

Klaassen, Curtis D.; Watkins, John B.. Casarett & Doull’s Essentials of Toxicology, Third Edition (Lange) . McGraw-Hill Education. Kindle Edition.

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2
Q

transversions

A

where the change is purine for pyrimidine or vice versa.

Purines = Adenine and Guanine
Pyrimidine = Cytosine, Thymine, Uracil

Klaassen, Curtis D.; Watkins, John B.. Casarett & Doull’s Essentials of Toxicology, Third Edition (Lange) . McGraw-Hill Education. Kindle Edition.

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3
Q

nondisjunction

A

occurs when pairs of homologous chromosomes or sister chromatids fail to separate during meiosis

can occur during either meiosis I or II

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