GENE EXPRESSION II

Question 1

___________RNA contains the codons that specifies the sequence of amino acids in protein

Answer 1

messenger RNA

Question 2

________ RNA has the anticodon and the carrier of amino acid

Answer 2

transfer rna

Question 3

____________ becomes part of the ribosome

Answer 3

ribosomal RNA

Question 4

__________ RNA is involved in chromatin remodeling

Answer 4

long noncoding RNA

Question 5

____________ involved in removal of introns and splicing of exons

Answer 5

small nuclear RNA

Question 6

________ and _________ RNA modulates gene expression

Answer 6

micro and silencing

Question 7

gene is a segment of DNA that determines a single character or phenotype

Answer 7

gene

Question 8

_________ is a segment of DNA that codes for protein or RNA

molecular definition

Answer 8

gene

Question 9

a section of a DNA or RNA molecule that codes for a specific polypeptide in protein synthesis

Answer 9

Cistrons

Question 10

coding segments of the gene

Answer 10

exons

Question 11

intervening segments of DNA that do not code for the amino acid sequence of the polypeptide

Answer 11

Introns

Question 12

codes for polypeptides and RNA’s

Answer 12

structural genes

Question 13

non structural genes

_______– one that serves as a starting point for reading the genetic code

___________- one that synthesizes the repressor

Answer 13

operator gene
regulator gene

Question 14

a linear array of genes involved in a metabolic pathway e.g. lac operon and trp operon

Answer 14

operon

Question 15

smallest unit of genetic expression codes for a subunit of a protein
(one cistron, one subunit concept)

Answer 15

cistron

Question 16

single mRNA that encodes more than one separately translated protein

Answer 16

polycistronic mRNA

Question 17

__________– describes how two adjacent genes involved in lactose metabolism were coordinately regulated by a genetic element located at one end of the gene cluster

Answer 17

lac operon

Question 18

structural gene for beta galactosidase which hydrolyze lactose to galactose and glucose

Answer 18

Lac Z gene

Question 19

structural gene for permease which transports lactose into the cell

Answer 19

lac Y gene

Question 20

encodes a thiogalactoside transacetylase which modify toxic galactoside to facilitate their removal from the cell

Answer 20

lac A gene

Question 21

_____________ is the principal enzyme involved in transcription

Answer 21

RNA polymerase

Question 22

the ___________ enzyme of RNA polymerase consists of 2 alpha and 2 beta and 1 omega subunits

Answer 22

core enzyme

Question 23

types of mammalian RNA polymerases

insensitive to amanitin
synthesizes rRNA

Answer 23

RNAP I

Question 24

types of mammalian RNA polymerases

sensitive to low concentration of amanitin

synthesizes hnRNA

Answer 24

RNAP II

Question 25

types of mammalian RNA polymerases sensitive to high concentrations of amanitin from amanita phalloides synthesizes tRNA

Answer 25

RNAP III

Question 26

BASICS STEPS IN TRANSCRIPTION recognition of specific binding site in the DNA template

Answer 26

template binding

Question 27

BASICS STEPS IN TRANSCRIPTION ( template binding) DNA strand that is transcribed into an RNA

Answer 27

template strand

Question 28

BASICS STEPS IN TRANSCRIPTION (template binding) the untranscribed DNA strand

Answer 28

coding (sense) strand

Question 29

BASICS STEPS IN TRANSCRIPTION alignment of 1st 2 NTP's to their complementary bases on the DNA template

Answer 29

chain initiation

Question 30

BASICS STEPS IN TRANSCRIPTION DNA template contains stop signals 2 major termination strategies Rho dependent Rho independent

Answer 30

termination and release

Question 31

inhibition that bind to the DNA template ____________ - antibiotic ____________ - derived from fungus

Answer 31

actinomycin D aflatoxin

Question 32

inhibitors that bind to RNA polymerase _________ - anti TB drug _________ - toxic principle found in poisonous mushroom

Answer 32

rifampicin amanitin