Gastrointestinal Tract

Question 1

This syndrome is composed of upper esophageal webs, iron deficiency anemia, and glossitis.

Answer 1

Plummer-Vinson Syndrome

Question 2

These are longitudinal mucosal tears near the gastroesophageal junction (GEJ) associated with severe retching or vomiting secondary to acute alcohol intoxication.

Answer 2

Mallory-Weiss Tears

Question 3

What is the hallmark of Baret Esophagus?

Answer 3

Presence of Goblet cells within the squamous epithelium of the esophagus.

Question 4

This stomach condition is characterized by having a thickened stiff wall with flattened rugae and is associated with diffuse infiltrative gastric carcinoma?

Answer 4

Linitis plastica

Question 5

What is the most common site for neuroendocrine tumors (NETs) ?

Answer 5

Small intestine

Question 6

Neuroendocrine tumors found in which part of the body tend to be multiple and aggressive?

Answer 6

Midgut ( Jejunum & Ileum )

Question 7

What is considered as a risk factor for Crohn’s disease but is a protective factor for ulcerative colitis?

Answer 7

Smoking

Question 8

What immunohistochemical marker is characteristic of gastrointestinal stromal tumors (GISTs) ?

Answer 8

CD117

Question 9

What is the common malignancy in gastrointestinal tract?

Answer 9

Colorectal adenocarcinoma

Question 10

What gene is known as the gatekeeper of colonic neoplasia due to being one of the earliest mutational events that leads to the progression of colorectal cancer?

Answer 10

APC

Question 11

This condiction occurs when mucinous tumors of the appendix spreads to the peritoneum , causing build-up of semisolid mucin in the abdomen.

Answer 11

Pseudomyxoma peritonei

Question 12

Management of Crohn’s disease?

Answer 12

Steroids
Surgery
Immunomodulators

Question 13

34/ F with pain felt shortly after meals without nocturnal awakening from pain. Gastric pH is increased. Endoscopy shows ulcer located at the corpus.

Answer 13

Gastric ulcer

Question 14

34/ F with pain felt hours after meals with nocturnal awakening from pain. Gastric pH is decreased. Endoscopy shows ulcer located at the antrum.

Answer 14

Doudenal ulcer

Question 15

39/ M case of Gastro esophageal reflux disease underwent endoscopy. Findings shows salmon colored plaques. Microscopic examination show goblet cells in gastric foveolar epithelium. Diagnosis?

Answer 15

Barrett Esophagus

Question 16

Characteristic gross appearance of diffuse-type of gastric cancer.

Answer 16

Linitis plastica

Question 17

Most common mesenchymal tumor of the gastrointestinal tract?

Answer 17

Gastrointestinal Stromal Tumor

Question 18

Cause of intestinal obstruction found in up to 5% of the population

Answer 18

Acquired hernia

Question 19

Site of carcinoid tumors with worst prognosis?

Answer 19

Small intestine ( Jejunum , Ileum)

Question 20

Inflammatory bowel disease with skip lesions , transmural inflammation, strictures, deep ulcers and noncaseating granulomas?

Answer 20

Crohn Disease

Question 21

Inflammatory bowel disease where smoking is beneficial?

Answer 21

Ulcerative colitis

Question 22

Gross findings in patients with Achalasia is?

Answer 22

Narrowed distal esophagus with dilatation of the proximal part

Question 23

T2 lesion seen in Sigmoid adenocarcinoma means?

Answer 23

Involvement of the muscularis propia

Question 24

What gastric biopsy results would most likely indicate gastric cancer?

Answer 24

Heaped up mucosal margins

Question 25

Which risk factor is associated with development of esophageal cancer?

Answer 25

Ingestion of caustic liquid

Question 26

In performing biopsies on palpable lesions, which microscopic finding is more likely indicative that the lesion is malignant?

Answer 26

Invasion to adjacent tissues

Question 27

Distance of incisors to LES?

Answer 27

32-50 (40) cm

Question 28

Esophageal biopsy showing intestinal metaplasia within the esophageal squamous mucosa?

Answer 28

Barrett Esophagus

Question 29

Recto-vaginal fistula would most likely to arise from?

Answer 29

Crohn’s Disease

Question 30

Which of the following phases of alkali caustic injury is the part where esophagus is the weakest?

Answer 30

Ulceration and Granulation

Question 31

Histopathologic type of cancer in the mid esophagus is?

Answer 31

Adenocarcinoma

Question 32

Middle aged man with recurrent epigastric pain occurring 1-3 hrs after meals and is worst at night. Was rushed to the ER one night due to severe pain on the back and chest. What’s your diagnosis?

Answer 32

Perforated Peptic Ulcer

Question 33

Common radiographic finding of perforated peptic ulcer showing subdiaphragmatic air?

Answer 33

Pneumoperitoneum

Question 34

Pathologic findings in achalasia are best described by?

Answer 34

Increased lower esophageal sphincter tone due to cholinergic signaling

Question 35

In the case of chronic gastric ulcer, the lesion destroys the serosal surface of the stomach wall and produce a red granular exudate which is described as?

Answer 35

Fibrinopurulent

Question 36

Microscopic changes occurring in distal esophagus with 5-year history of GERD.

Answer 36

Squamous ( basal) cell hyperplasia

Question 37

Involvement of the left supraclavicular node by metastasis from stomach?

Answer 37

Virchow node

Question 38

Stomach CA metastasis to ovaries ( bilateral) Characterized by abundant mucin-secreting , signet ring cells.

Answer 38

Krukenberg tumor

Question 39

Subcutaneous periumbilical metastasis of stomach CA.

Answer 39

Sister Mary Joseph Nodule

Question 40

Palpable mass on Digital Rectal Exam suggesting metastasis to rectouterine pouch ( pouch of Douglas)

Answer 40

Blumer shelf