Feline Theriogenology Flashcards

1
Q

puberty in cats; when, what its influenced by

A

◦ Pubertal estrous = between 4 – 12mnts of age
◦ Influenced by time of year & body condition
◦ Usually when reaches 80% of adult body weight

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2
Q

what type of ovulators are cats

A

◦ Seasonal, polyestrous, induced ovulator
◦ Induced ovulators = require copulation to initiate the LH surge

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3
Q

when does the estrus cycle occur

A

◦ Estrus cycles occur at 4-30 day intervals in cats exposed to constant daylight (14 hrs)

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4
Q

prolonged anestrus in cats

A

◦ Prolonged anestrus = decreasing or short day lengths (autumn)

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5
Q

feline estrous cycle begins vs peak

A

◦ Season begins Jan-Feb = peak is Feb-March

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6
Q

what can be used to stop intact queens from cycling

A

melatonin

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7
Q

what happens during proestrus; behaviour, estrogen level, length

A

◦ Only observed in minority of queens = most enter estrus directly
◦ Males are attracted but females are non-responsive
◦ Continuous rubbing of head and neck
◦ Short lived - if it occurs at all (0.5-2 days)
◦ Increase in estrogen

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8
Q

what do we see with behavioural estrus

A

◦ Crouching in the front with hind end elevated = lordosis
◦ Threading with hind legs, deviation of the tail = vulva exposed for mating
◦ Vocalize, more head rubbing, affectionate behavior

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9
Q

when does estrus occur

A

◦ Occurs during peak follicular activity & estradiol concentrations

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10
Q

what stage of the cycle are cats receptive to mating

A

estrus

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11
Q

how can you detect estrus (4)

A

◦ Estrus behavior

◦ Vulvar labia will only slightly increase in size compared to the bitch

◦ Mucoid discharge can be seen – won’t see bloody vaginal discharge

◦ Vaginal cytology = see cornification as in the bitch (Not useful to tell you when to breed)

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12
Q

what are the steps of mating

A

◦ Nose to nose
◦ Investigate perineal area – Flehmen
◦ Grab neck – very important
◦ Mount
◦ Threading – slides down the female
◦ Pelvic thrusting -> intromission -> ejaculation -> 20 seconds
◦ Pulls away quickly -> avoid being struck by female
◦ Queen licks vulva, rubs on the floor, vocalizes = “after reaction”

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13
Q

duration of estrus

A

◦ Variable
◦ Average: 5.8 days (Range: 2-19 days)

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14
Q

LH surge; induced by, what magitude depends on, when ovulation occurs after

A

◦ Induced by copulation but requires hypothalamic/pituitary exposure to estrogen
◦ Needs to be in heat
◦ Magnitude of LH surge increases with number of copulations
◦ Induction of ovulation occurs 29-40hrs later -> ovulation occurs 24-48hrs post coitus

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15
Q

does copulation cause ovulation

A

copulation causes the LH surge = NOT ovulation

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16
Q

when does diestrus occur

A

◦ Follows estrus in the queen that has ovulated (induced or spontaneous ovulation)

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17
Q

how long does diestrus last

A

Lasts approx. 40 days in pseudopregnant queen
◦ Note: pseudopregnancy is often not visible externally in comparison to bitches

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18
Q

what ends diestrus

A

◦ Ends with luteolysis (mechanism unknown in the cat)

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19
Q

what hormone is dominant in diestrus

A

◦ Progesterone dominated -> CLs
◦ Progesterone starts to rise from baseline within 24 hrs post-ovulation

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20
Q

what is the interestrus interval; what happens during it, length

A

◦ Period that follows one estrus and precedes the next in queens that have not been induced to ovulate
◦ Estradiol drops
◦ No sexual behavior or receptivity is present
◦ Length is variable

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21
Q

optimal breeding time

A

◦ Between 1.5-7 years of age

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22
Q

why do we need to bloodtype cats

A

◦ Important for prevention of neonatal isoerythrolysis
◦ Should blood type all cats used in breeding colony/program
◦ Purebred cats (British Shorthair, Devon & Cornish Rex) = more type B

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23
Q

breeding of female in males territory

A

◦ Ideally don’t breed day 1 of estrus
◦ Then starting on day 2, breed 3-4x daily until end of estrus, if possible (at least over 2 day
period)

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24
Q

type of placentation

A

◦ Endotheliochorial, zonary
◦ No obvious marginal hematomas

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25
Q

length of pregnancy

A

◦ 63-66 days, on average, from rise in P4
◦ 56-69 days from mating

26
Q

what type of hormone is present during pregnancy

A

Progesterone dependent
◦ CLs

27
Q

when does prolactin increase

A

Unlike in dogs – our prolactin only increases if pregnant – during the last
3rd of pregnancy and during lactation

28
Q

pregnancy diagnosis (5) and when we can do them

A

Lack of estrus behavior
◦ Pseudopregnancy
◦ Some cats display estrus even while pregnant

Pinking of the nipples
◦ Occurs day 14-18

Abdominal palpation
◦ Day 25-30

Radiographs
◦ As with bitches

Ultrasound
◦ Easy by day 24-25

29
Q

what happens in stage 1 of queening

A

Stage 1: cervical dilation/uterine contractions
◦ Restlessness is the most common sign

30
Q

what happens in stage 2 of queening

A

Stage 2: passage of fetuses
◦ Kitten should be delivered within 15 mins once noted at vulvar lips
◦ Can take a very long time (interruptions by 10-12 hours are possible)

31
Q

what happens in stage 3 of queening

A

Stage 3: passage of fetal membranes

32
Q

is P4 drop a prereq for queening

A

Progesterone drops, but doesn’t necessarily have to = the drop isn’t a prerequisite for onset of parturition
◦ Don’t see a temperature drop like in bitches

33
Q

how common is dystocia in cats

A

overall uncommon

34
Q

what type of cats are at increased risk of dystocia

A

Purebred cats at increased risk
◦ Dolicocephalic and brachycephalic breeds = obstructive dystocia

35
Q

what is the next step if there is no response to 2 oxytocin symptoms

A

c section

36
Q

medical management of dystocia

A

Medical management -> oxytocin & calcium gluconate
◦ Cannot do manipulations à too small
◦ Same “rules” apply as in dogs (no obstructive dystocias, FHRs, etc.)
◦ “Quiet” place, left alone

37
Q

surgical management of dystocia

A

Surgical management -> c-section
◦ Pre-medicate queen at last minute = kittens hard to resuscitate

38
Q

most likely cause of dystocia in cats

A

uterine torsion

39
Q

PP issues in cats (7)

A

Retained fetal membranes = metritis
◦ Usually queen is good at cleaning – don’t see much in terms of discharge
◦ If note discharge >7 days post-partum = investigate

Mastitis

Hypocalcemia

Agalactia
◦ Sometimes can’t express milk – kittens are still gaining weight & healthy – not truly agalactia

Uterine prolapse à more common in cats

SIPS

Poor mothering

40
Q

when does cycling occur again after PP

A

Within 2 weeks post-partum à begin cycling again
◦ Anovulatory cycles; at least @ start of lactation = become ovulatory as
lactation decreases

41
Q

specific disorders common in cats (5)

A

◦ Benign mammary hypertrophy/hyperplasia
◦ Mammary neoplasia
◦ Cystic endometrial hyperplasia (CEH)/pyometra complex
◦ Ovarian cysts
◦ Ovarian remnant syndrome

42
Q

diagnosis of benign mammary hypertrophy/hyperplasia

A

◦ Signalment
◦ Clinical signs
◦ Progesterone assay
◦ Biopsy in older cats to rule out neoplasia

43
Q

treatment benign mammary hypertrophy/hyperplasia

A

Removal of progesterone source
◦ OHE, aglepristone, luteolysis or abortion (spontaneous)

44
Q

when (age) is benign mammary hypertrophy/hyperplasia common

A

Common in young cats (13 weeks- 2 years)

45
Q

what hormone is benign mammary hypertrophy/hyperplasia dependent on

A

Progesterone dependent condition
◦ Occurs following ovulation (pregnant or not)

46
Q

what treatment can cause benign mammary hypertrophy/hyperplasia

A

Can be seen in neutered males/spayed females if treated w progestins!

47
Q

what does benign mammary hypertrophy/hyperplasia look like

A

See asymmetrical, firm, rapidly growing mammary tissue
◦ Can become bruised & ulcerated as they enlarge

48
Q

3rd most common tumor in cats

A

Mammary neoplasia but still overall not seen a lot

49
Q

risk of mammary neoplasia in intact female cats

A

Intact = 7x greater chance of developing mammary neoplasia

50
Q

clinical signs of mammary neoplasia

A

◦ Older cats
◦ 1 or more masses (can have L and R mammary chain involvement)
◦ Are firm, can be well or poorly demarcated nodules (several mm to
10cm)
◦ Swollen nipples +/- exudate
◦ Ropy lymphatics

51
Q

does mammary neoplasia metastasize usually

A

High rates of metastasis
◦ Malignant adenocarcinoma
◦ Occurs in 50-90% of cases

52
Q

diagnosis of mammary neoplasia

A

◦ Tumor histology (FNA, biopsy)

53
Q

treatment of mammary neoplasia

A

◦ Surgery
◦ Chemotherapy
◦ Radiation
Important to do metastasis check

54
Q

clinical signs of cystic endometrial hyperplasia/pyometra

A

◦ Not cycling
◦ Depression, lethargy
◦ PU/PD
◦ Distended abdomen, vomiting
◦ +/- vaginal discharge

55
Q

diagnosis and treatment of cystic endometrial hyperplasia/pyometra

A

very similar to in bitches

56
Q

treatment of ovarian cysts

A

◦ Luteinization with hCG (induce ovulation)
◦ Surgical drainage
◦ OHE

57
Q

diagnosis of ovarian cysts

A

◦ Ultrasound

58
Q

what is true persistent estrus hard to distinguish from

A

True persistent estrus – like those caused by ovarian cysts – can be hard to distinguish from a normal cat
(overlapping follicular growth)

59
Q

what happens if cyst cells are secreting estrogen

A

◦ Persistent estrus
◦ Or can have no clinical signs (no estrogen secretion)

60
Q

how can infertility in queens be categorized

A

◦ Persistent anestrus
◦ Persistent estrus
◦ Cycling queens that refuse copulation with the male
◦ Cycling queens that fail to conceive after copulation with a fertile male; 1st step is to determine if they ovulated

61
Q

causes of EED/abortion in cats (8)

A
  • FIP
  • Feline Herpes Virus
  • FeLV
  • Panleukopenia
  • Toxoplasma
  • Salmonella
  • Chlamydophila
  • Mycoplasma
62
Q

what should we consider management wise in differentials

A

◦ Season? Photoperiod?
◦ Recent change in environment
◦ Partner discrimination
◦ Husbandry – vaccine status, deworming, etc.