Excitatory and Inhibitory neurones

Question 1

What type of channel are glutamate channels?

Answer 1

tetramers

Question 2

What type of channel are GABAa; glycine and nicotinic ACh channels?

Answer 2

pentamers

Question 3

How are ionotropic glutamate receptors classified?

Answer 3

by their response to non-endogenous agonists that mimic glutamtate

Question 4

What are the two type of ionotropic glutamate receptor?

Answer 4

NMDA and non-NMDA

Question 5

What are NMDA receptrs permeable to?

Answer 5

Na; Ca and K

Question 6

What agonists do non-NMDA receptors bind to?

Answer 6

kainic acid and AMPA

Question 7

What are non-NMDA receptors permeable to?

Answer 7

Na and K

Question 8

What is the difference between NMDA and non-NMDA receptors?

Answer 8

non-NMDA receptors mediate fast excitatory synpatic transmission whereas NMDA receptors contribute a slow component to excitatry synaptic potenetial

Question 9

What type of receptor are GABAa receptors?

Answer 9

ionotropic

Question 10

What type of receptor are GABAb receptors?

Answer 10

metabotropic

Question 11

What are GABAa receptors permeable to?

Answer 11

chloride

Question 12

What channels do GABAb receptors activate?

Answer 12

K

Question 13

What are glycine receptors permeable to?

Answer 13

Cl

Question 14

What is the usual action of metabotropic receptrs?

Answer 14

modulatory synaptic