Exam 3 Weekly Review Questions Flashcards
What is the most frequent cause of death in a patient with multiple myeloma?
Infectious diseases
Cryoglobulins are proteins that precipitate or gel at:
0 C
Patients with Waldenstrom macroglobulinemia exhibit abnormally large amounts of:
IgM
Light chain disease represents about ___ of monoclonal gammopathies.
10-15%
MGUS is characterized by all of the following except:
Presence of lytic bone lesions
Typical lab results seen in lymphoid chronic thyroiditis are:
Increased TSH, decreased T3 and T4, anti-TPO antibodies present
Which type of cells are responsible for initiating immune response to islet cells in Type 1 Diabetes:
CD4+ T cells
Autoimmune hepatitis is most common in:
Young women
T/F: B cells undergo a second process of selection during their maturation.
True
T/F: The thyroid is responsible for deleting autoreactive T cells that have the potential to cause autoimmune disease.
False, the thymus is responsible
One of the most frequent causes of drug-induced lupus is:
Procainamide hydrochloride
SLE is more common in:
Adolescent through middle aged women
Patients with SLE typically manifest:
Butterfly rash over the bridge of the nose
Rheumatoid arthritis is known to be caused by genetic issues.
False, the exact cause is unknown
Arrange the steps of pathogenesis of rheumatoid arthritis in the correct order:
- Initiation of synovitis by the primary causative factor
- Subsequent immunologic events that perpetuate the initial inflammatory response
- Transition of an inflammatory reaction in the synovium to a proliferative, destructive tissue process
