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Immuno > CH 17 - Infectious Mononucleosis > Flashcards

CH 17 - Infectious Mononucleosis Flashcards

1
Q

EBV can cause all the following except:

  • Infectious mononucleosis
  • Burkitt lymphoma
  • Nasopharyngeal carcinoma
  • Neoplasms of the bone marrow
A

Neoplasms of the bone marrow

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2
Q

The primary mode of EBV transmission is:

A

Exposure to oral-pharyngeal secretions

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3
Q

Infants infected with EBV are more likely to experience symptomatic infection than EBV-infected adolescents.

A

False

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4
Q

IgM heterophile antibody is characterized by all of the following features except:

  • Reacts with horse, ox, and sheep RBCs
  • Absorbed by beef erythrocytes
  • Absorbed by guinea pig kidney cells
  • Does not react with EBV-specific antigens
A

Absorbed by guinea pig kidney cells

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5
Q

Characteristics of EBV-infected lymphocytes include all of the following except:

  • B type
  • Expression of viral capsid antigen
  • Expression of early antigen
  • Expression of EBV genome
A

Expression of EBV genome

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6
Q

What stages of infectious mononucleosis infection is characterized by antibody to Epstein-Barr nuclear antigen (EBNA)?

A
  1. Past infection (convalescent) period

AND

  1. Reactivation of latent infection
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7
Q

Which of the following stages of infectious mononucleosis infection is/(are) characterized by heterophile antibody?

A
  1. Recent (acute) infection

AND

  1. Reactivation of latent infection
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8
Q

What percentage of the world’s population is exposed to EBV?

A

95%

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9
Q

Infectious mononucleosis postperfusion syndrome is a primary infection resulting from a blood transfusion from a(n) _______ to a(n) _______ recipient.

A

Immune; nonimmune

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10
Q

In infectious mononucleosis, there is no:

A

Carrier state

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11
Q

The incubation period of infectious mononucleosis is:

A

10 to 50 days

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12
Q

The use of horse erythrocytes in rapid slide tests for infectious mononucleosis increases their:

A

Sensitivity AND Specificity

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13
Q

EBV-infected B lymphocytes express all the following new antigens except:

  • Viral capsid antigen (VCA)
  • Early antigen (EA)
  • Cytoplasmic antigen (CA)
  • Nuclear antigen (NA)
A

Cytoplasmic antigen (CA)

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14
Q

Anti-EBNA IgG does not appear until a patient has entered the:

A

Convalescent period

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15
Q

An appropriate description of the Paul-Bunnell screening test is:

A

Detects heterophile antibodies and uses sheep erythrocytes

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16
Q

An appropriate description of the Davidsohn differential test is:

A

Distinguishes between heterophile antibodies; uses beef erythrocytes, guinea pig kidney cells, and sheep erythrocytes

17
Q

An appropriate description of the MonoSlide agglutination test is:

A

Detects heterophile antibodies and uses horse erythrocytes

Immuno (23 decks)

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