CH 4 - Cellular Activities Flashcards
Arrange the steps of phagocytosis in the proper sequence.
1) Increase in chemoattractants at site of tissue damage
2) Change in direction of movement due to chemoattractant substance
3) Ingestion of bacteria
4) Digestion of bacteria
The function of polymorphonuclear neutrophil (PMN)
leukocytes is:
Primary phagocytic cells
Mast cells are associated with:
Participation in IgE hypersensitivity reactions
Chronic granulomatous disease represents a defect of:
Oxidative metabolism
An alteration of phagocytic killing is associated with:
Corticosteroid therapy
A defective monocyte cytotoxicity is associated with:
Wiskott-Aldrich syndrome
A defective release of macrophage-activating factors is
associated with:
Intracellular infections
A depressed migration is associated with:
Burns or diabetes
Impaired phagocytosis is associated with:
Systemic lupus erythematosus
A characteristic of chronic granulomatous disease is:
Failure to exhibit increased anaerobic metabolism during
phagocytosis
A characteristic of lazy leukocyte syndrome is:
Defective leukocyte locomotion
A characteristic of Chédiak-Higashi anomaly (syndrome) is:
Marked defect in cellular response to chemotaxis
A characteristic of myeloperoxidase deficiency is:
Mild-to-marked defect in bactericidal ability of neutrophils
Which statement about mast cells is correct?
- They have a low concentration of heparin in the granules
- They have a high concentration of histamine in the granules
- They react with two adjacent IgA molecules on mast cells
- They are not associated with anaphylactic shock
They have a high concentration of histamine in the granules
A function of the cell-mediated immune response not
associated with humoral immunity is:
- Defense against viral and bacterial infection
- Initiation of rejection of foreign tissues and tumors
- Defense against fungal and bacterial infection
- Antibody production
Initiation of rejection of foreign tissues and tumors
All of the following are a function of T cells except:
- Mediation of delayed-hypersensitivity reactions
- Mediation of cytolytic reactions
- Regulation of the immune response
- Synthesis of antibody
Synthesis of antibody
The function of T cells is:
Cellular immune response
The function of B cells is:
Humoral response
The function of natural killer (NK) cells is:
Antibody-dependent, cell-mediated cytotoxicity (ADCC)
reaction
Natural killer cells:
Mediate viral immunity
The surface membrane marker for CD4 is:
Helper-inducer T cells
The surface membrane marker for CD8 is:
Suppressor-cytotoxic T cells
The surface membrane marker for CD3 is:
All or most T lymphocytes
All of the following are B cell surface membrane markers
except:
- sIg
- Fc receptor
- C3 receptor
- CD4
CD4
The process of aging causes the thymus to:
- Decrease in size
- Lose cellularity
T lymphocytes can also be referred to as:
Memory cells
Which of the following is not a characteristic of T lymphocytes?
Can synthesize and secrete immunoglobulin
The appropriate function of T lymphocytes is:
Cellular immune response
The appropriate function of B lymphocytes is:
Humoral antibody response
The appropriate function of cytotoxic or effector T cells is
related to/associated with:
- Directly destroying target cells
- Transplanted organ rejection
- CD4+ marker
The appropriate function of helper or regulator T cells is:
- To activate macrophages
- To stimulate cell growth and differentiation
- Antibody production and secretion of cytokines
