CH 4 - Cellular Activities Flashcards
Arrange the steps of phagocytosis in the proper sequence.
1) Increase in chemoattractants at site of tissue damage
2) Change in direction of movement due to chemoattractant substance
3) Ingestion of bacteria
4) Digestion of bacteria
The function of polymorphonuclear neutrophil (PMN)
leukocytes is:
Primary phagocytic cells
Mast cells are associated with:
Participation in IgE hypersensitivity reactions
Chronic granulomatous disease represents a defect of:
Oxidative metabolism
An alteration of phagocytic killing is associated with:
Corticosteroid therapy
A defective monocyte cytotoxicity is associated with:
Wiskott-Aldrich syndrome
A defective release of macrophage-activating factors is
associated with:
Intracellular infections
A depressed migration is associated with:
Burns or diabetes
Impaired phagocytosis is associated with:
Systemic lupus erythematosus
A characteristic of chronic granulomatous disease is:
Failure to exhibit increased anaerobic metabolism during
phagocytosis
A characteristic of lazy leukocyte syndrome is:
Defective leukocyte locomotion
A characteristic of Chédiak-Higashi anomaly (syndrome) is:
Marked defect in cellular response to chemotaxis
A characteristic of myeloperoxidase deficiency is:
Mild-to-marked defect in bactericidal ability of neutrophils
Which statement about mast cells is correct?
- They have a low concentration of heparin in the granules
- They have a high concentration of histamine in the granules
- They react with two adjacent IgA molecules on mast cells
- They are not associated with anaphylactic shock
They have a high concentration of histamine in the granules
A function of the cell-mediated immune response not
associated with humoral immunity is:
- Defense against viral and bacterial infection
- Initiation of rejection of foreign tissues and tumors
- Defense against fungal and bacterial infection
- Antibody production
Initiation of rejection of foreign tissues and tumors
