CH 15 - Syphillis

Question 1

Treponema pallidum (T. pallidum) is the causative organism associated with the disease:

Answer 1

Syphilis

Question 2

Treponema pallidum (T. pallidum) variant is the causative organism associated with the disease:

Answer 2

Bejel

Question 3

Treponema pertenue (T. pertenue) is the causative organism associated with the disease:

Answer 3

Yaws

Question 4

Treponema carateum (T. carateum) is the causative organism associated with the disease:

Answer 4

Pinta

Question 5

In the primary stage of syphilis, a clinical finding is:

Answer 5

Development of a chancre

Question 6

In the secondary stage of syphilis, a clinical finding is:

Answer 6

Generalized illness followed by macular lesions in most patients

Question 7

In the latent stage of syphilis, a clinical finding is:

Answer 7

Diagnosis only by serologic methods

Question 8

In the late (tertiary) stage of syphilis, a clinical finding is:

Answer 8

Presence of gummas

Question 9

Which of the following is a term for nontreponemal antibodies produced by an infected patient against components of their own or other mammalian cells?

Answer 9

Reagin antibodies

Question 10

The FTA-ABS test is a:

Answer 10

Treponemal method

Question 11

The TP-PA test is a:

Answer 11

Treponemal method

Question 12

The RPR test is a:

Answer 12

Nontreponemal method

Question 13

In the RPR procedure, a false-positive reaction can result from all the following except:

• Infectious mononucleosis
• Leprosy
• Rheumatoid arthritis
• Streptococcal pharyngitis

Answer 13

Streptococcal pharyngitis

Question 14

The first diagnostic blood test for syphilis was the:

Answer 14

Wassermann

Question 15

Syphilis was initially treated with:

Answer 15

Heavy metals (e.g., arsenic)

Question 16

Direct examination of the treponemes is most often performed by:

Answer 16

Darkfield microscopy

Question 17

Pathogenic treponemes _______________ cultivatable with consistency in artificial laboratory media.

Answer 17

Are not

Question 18

In infected blood, T. pallidum does not appear to survive at 4°C (39°F) for longer than:

Answer 18

3 days

Question 19

The primary incubation period for syphilis (T. pallidum) is usually about:

Answer 19

3 weeks

Question 20

The stage of syphilis that can be diagnosed only by serologic (laboratory) methods is the:

Answer 20

Latent phase

Question 21

Immunocompetent patients infected with T. pallidum produce:

Answer 21

1. Specific antibodies against T. pallidum

AND

2. Nonspecific antibodies against the protein antigen group common to pathogenic spirochetes

AND

3. Reagin antibodies