Exam 3- Alterations Of Leukocte, Lymphoid, And Hemostatuc Function Flashcards
Lymphadenopathy
Enlarged lymph nodes.
When localized, indicates drainage from areas of information.
When generalized, indicates a malignant or non-malignant disease.
Neutropenia
Lower than normal neutrophil count in the blood.
Pancytopenia
Lower than normal blood counts of white blood cells, red blood cells, and platelets.
Leukocytosis
Higher than normal white blood cell count.
Leukopenia
Lower than normal white blood cell count.
Causes increased risk for infection.
Granulocytosis
Higher than normal blood counts of neutrophils, eosinophils, and basophils.
Agranulocytosis
Complete absence of neutrophils, eosinophils, and basophils in the blood.
Eosinophilia
And increased number of eosinophils in the blood.
The most common causes are parasites, toxic foreign particles, and hypersensitivity reactions.
Monocytosis
And increased number of monocytes.
Occurs during the late phase of inflammation
Neutrophilia
And increase number of neutrophils in the blood.
Occurs during the early phase of information.
Leukemia
Cancers of blood-forming clots
All types are characterized by uncontrolled production of white blood cells in the bone marrow that fair by decreases the amount and function of erythrocytes and platelets.
Lymphoblastic
Used to describe a leukemia or lymphoma, and means that the malignant cells are immature.
Thrombocythemia
a rare chronic blood disorder characterised by the overproduction of platelets by megakaryocytes in the bone marrow.
Increases the risk for clotting.
HIT
Heparin induced thrombocytopenia.
When a person develops HIT antibodies, they react with the PF4- heparin complex. The FC end of the antibodies bind to platelets FC receptors, activating the platelets, which release substances that promote clotting. This causes thrombocytopenia by using up platelets to form microclots, extension of previous clots, and new clots.
Platelet factor 4 (PF4)
And activated platelet. Binds to heparin.
Lymph Oma
Cancers of lymphatic tissues.
Lymphocytic leukemia
Arises from the lymphoid cell line that normally produces B and T lymphocytes and natural killer cells.
Myelogenous leukemia
Arises from the myeloid cell line that normally produces granulocytes, monocytes, erythrocytes, and platelets.
Splenomegaly
Enlargement of the spleen.
Can be secondary to infection and increase the risk for spleen rupture from blunt trauma.
Hypersplenism
Over activity of the spleen in response to splenomegaly.
Arterial thrombi
Composed primarily of platelet aggregates held together by strands of fibrin.
Venus thrombosis
Composed primarily of erythrocytes, greater amounts of fibrin, and fewer platelets.
Antiphospholipid antibody
Auto antibody against plasma membrane components that causes hypercoagulability by binding to platelets and endothelial cells.
M protein
Abnormal antibody released by malignant plasma cells in multiple myeloma.