Exam 2- Stress And Disease Flashcards
Stress
Demand exceeds a person’s coping abilities. Begins with a stimulus the brain perceives as stressful and in turn promotes adaptational and survival-related physiologic responses. These responses can become deregulated and cause pathophysiology.
Activation of the sympathetic nervous system
Increased heart rate and contractility, increased blood pressure, increased blood glucose, increase sphincter tone and gastrointestinal tract, increased diameter of bronchioles, decreased skin bloodflow, decreased peristalsis and gastrointestinal tract
General adaptation syndrome
Nonspecific response to noxious physiologic stimuli
The alarm stage: The central nervous system is aroused.
stage of resistance or agitation: Choice to either fight or flight.
state of exhaustion: continuous stress causes the progressive breakdown of compensatory mechanisms and homeostasis. Exhaustion marks the onset of certain diseases.
Post dramatic stress disorder
Occurs in response to memory of Trumatic events, where as a conditioned response occurs in response to anticipation of Trumatic events
Coping
The process of managing stressful to mans and challenges that are appraised as texting or exceeding and individuals resources
Cortisol
Increases blood glucose and secretion of gastric acid.
Has an anabolic affect on protein metabolism in the liver and a catabolic effect and muscle and other tissues
And high levels can cause poor wound healing.
Sleep deprivation
Increases cortisol levels in blood before the usual bedtime, increases blood pressure, increases blood glucose, increases pro inflammatory cytokines, decreases activity at parasympathetic neurons
Acute stress
Can be immunoenhancing
Stress
When a physiological or psychological demand exceeds and individuals coping abilities
Psychoneuroimmunology
The study of how consciousness the nervous system and the immune system interact
Corticotropin releasing hormone
Released by the hypothalamus. Activates both the HPA axis and a sympathetic system
Adrenal Medulla
An extension of the sympathetic nervous system
Norepinephrine
Promotes arousal, increased vigilance, and increased anxiety.
Allostatic load
The cumulative effects of physiologic responses to stressors
Oxytocin
I hormone which has increased released during response to stressors is believed to promote social attachment