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Pharmacology 1 > Exam 2: Injectable Anesthetics > Flashcards

Exam 2: Injectable Anesthetics Flashcards

1
Q

What are the 3 categories of Injectable anesthetics?

A
  1. Dissociative anestheticss
  2. Barbiturates
  3. Non Barbiturates
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2
Q

What are the 2 dissociative anesthetics

A
  1. Ketamine

2. Tiletamine

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3
Q

What are the 2 subcategories of Barbiturates?

A
  1. Thiobarbiturates

2. Oxybarbitrates

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4
Q

What is the drug classified as a thiobarbiturate?

A

Thiopental

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5
Q

What are the 2 drugs in the subcategory Oxybarbiturate

A
  1. Phenobarbital

2. Pentobarbital

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6
Q

What are the 3 Non-Barbiturates?

A
  1. Propofol
  2. Alfaxalone
  3. Etomidate
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7
Q

Drug-induced central depression resulting in unconsciousness

A

General Aneshtesia

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8
Q

Drug- induced dissociation of the thalamocortical and limbic systems resulting in a catatonic state

A

Dissociative anasthesia

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9
Q

Characterized by vountary motor excitment and state of analgesia

A

Analgesia

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10
Q

What are the 5 stages of Anesthesia

A
  1. Analgesia
  2. Excitment phase
  3. Surgical anesthesia
  4. Medullary paralysis
  5. Death
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11
Q

Characterized by involuntary excitation or delirium

A

Excitment phase

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12
Q

What is the MOA of ketamine and tiletamine

A

Non- competitive NMDA receptor antagonists

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13
Q

Dissociative Anesthetics inhibits _____

A

Glutamate

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14
Q

What part of the nociception pathway does Ketamine and Tiletamine act on?

A

Modulation

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15
Q

T/F Dissociative Anesthetics can cross the BBB

A

T

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16
Q

What are the two efects of Dissociative Anesthetics on the CNS?

A
  1. Depression of sensory preception

2. Activation of limbic system (emotional/behavioral/memory)

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17
Q

Dissociative Anesthetics Induce which stages of anesthesia?

A

Stages 1 and 2

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18
Q

T/F. Dissociative Anesthetics cause the animal to lose complete consciousness

A

F. partial

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19
Q

What are the main effects of Dissociative Anesthetics

A
  1. Catalepsy

2. Analgesia

20
Q

CVS effects of Ketamine and Tiletamine

A

Inc. CO and HR

21
Q

T/F. Ketamine is a controlled substance

A

T

22
Q

What scheduled drug is ketamine?

A

3

23
Q

T/F. Tiletamine is a controlled drug

A

F

24
Q

What is triple dip?

A

for large animals

Guaifenesin + Xylazine + Ketamine

25
Q

What is FLK

A

Fentanyl + Lidocaine + Ketamine

26
Q

What is MLK?

A

Morphine + Lidocaine + Ketamine

27
Q

What is Kitty magic?

A

Ketamine + Dexamedetomidine + Buprenorphine

28
Q

What parts of the nociception pathway do Barbituates act on?

A

Perception and Modulation

29
Q

What is the MOA of Barbituates

A

GABA agonists

30
Q

What is the main effets of Barbiturates

A

Sedation and hypnosis

31
Q

T/F. Barbiturates cause poor anesthesia

A

T

32
Q

T/F. Barbiturates have anticonvulsant effects

A

T

33
Q

CVS effects of Barbiturates

A

Hypotension due to Cardiac depression

34
Q

Resp. system effects of Barbiturates

A

Dose-Dependent resp. depression

35
Q

Ultra-Short acting Thiobarbiturate GABA receptor agonist

A

Thiopental

36
Q

used for euthanasia

A

Pentobarbital

37
Q

Propofol effects on CNS

A

Dose Dependent CNS Depression

38
Q

Propofol effects on CVS

A

Vasodilation and hypotension

39
Q

Propofol effects on Resp system

A

Dose dependent resp. depression

40
Q

What is the risk with givine propofol to cats?

A

Heinz-body anemia

41
Q

Most common non barbiturate

A

Propofol

42
Q

Non- barbiturate neurosteroid

A

Alfaxalone

43
Q

What is the MOA of Alfaxalone

A

GABA agonist

44
Q

1 non barbiturate choice for unstable patient

A

Etomidate

45
Q

T/F. you can uses Etomidate in animals with heart dz

A

T

46
Q

Which of the following should be avoided in patients with thraumatic brain injury

a. Diazepam
b. Propofol
c. Ketamine
d. Lidocaine

A

c. Ketamine

47
Q 
Which of the following is not considered an IV anesthetic induction agent?
a. Ketamine
b. Propofol
C. Alfaxalone
d. Fentanyl
A

D. Fentanyl

Pharmacology 1 (22 decks)

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