Exam 2: Injectable Anesthetics Flashcards
What are the 3 categories of Injectable anesthetics?
- Dissociative anestheticss
- Barbiturates
- Non Barbiturates
What are the 2 dissociative anesthetics
- Ketamine
2. Tiletamine
What are the 2 subcategories of Barbiturates?
- Thiobarbiturates
2. Oxybarbitrates
What is the drug classified as a thiobarbiturate?
Thiopental
What are the 2 drugs in the subcategory Oxybarbiturate
- Phenobarbital
2. Pentobarbital
What are the 3 Non-Barbiturates?
- Propofol
- Alfaxalone
- Etomidate
Drug-induced central depression resulting in unconsciousness
General Aneshtesia
Drug- induced dissociation of the thalamocortical and limbic systems resulting in a catatonic state
Dissociative anasthesia
Characterized by vountary motor excitment and state of analgesia
Analgesia
What are the 5 stages of Anesthesia
- Analgesia
- Excitment phase
- Surgical anesthesia
- Medullary paralysis
- Death
Characterized by involuntary excitation or delirium
Excitment phase
What is the MOA of ketamine and tiletamine
Non- competitive NMDA receptor antagonists
Dissociative Anesthetics inhibits _____
Glutamate
What part of the nociception pathway does Ketamine and Tiletamine act on?
Modulation
T/F Dissociative Anesthetics can cross the BBB
T
What are the two efects of Dissociative Anesthetics on the CNS?
- Depression of sensory preception
2. Activation of limbic system (emotional/behavioral/memory)
Dissociative Anesthetics Induce which stages of anesthesia?
Stages 1 and 2
T/F. Dissociative Anesthetics cause the animal to lose complete consciousness
F. partial
What are the main effects of Dissociative Anesthetics
- Catalepsy
2. Analgesia
CVS effects of Ketamine and Tiletamine
Inc. CO and HR
T/F. Ketamine is a controlled substance
T
What scheduled drug is ketamine?
3
T/F. Tiletamine is a controlled drug
F
What is triple dip?
for large animals
Guaifenesin + Xylazine + Ketamine
What is FLK
Fentanyl + Lidocaine + Ketamine
What is MLK?
Morphine + Lidocaine + Ketamine
What is Kitty magic?
Ketamine + Dexamedetomidine + Buprenorphine
What parts of the nociception pathway do Barbituates act on?
Perception and Modulation
What is the MOA of Barbituates
GABA agonists
What is the main effets of Barbiturates
Sedation and hypnosis
T/F. Barbiturates cause poor anesthesia
T
T/F. Barbiturates have anticonvulsant effects
T
CVS effects of Barbiturates
Hypotension due to Cardiac depression
Resp. system effects of Barbiturates
Dose-Dependent resp. depression
Ultra-Short acting Thiobarbiturate GABA receptor agonist
Thiopental
used for euthanasia
Pentobarbital
Propofol effects on CNS
Dose Dependent CNS Depression
Propofol effects on CVS
Vasodilation and hypotension
Propofol effects on Resp system
Dose dependent resp. depression
What is the risk with givine propofol to cats?
Heinz-body anemia
Most common non barbiturate
Propofol
Non- barbiturate neurosteroid
Alfaxalone
What is the MOA of Alfaxalone
GABA agonist
1 non barbiturate choice for unstable patient
Etomidate
T/F. you can uses Etomidate in animals with heart dz
T
Which of the following should be avoided in patients with thraumatic brain injury
a. Diazepam
b. Propofol
c. Ketamine
d. Lidocaine
c. Ketamine
Which of the following is not considered an IV anesthetic induction agent? a. Ketamine b. Propofol C. Alfaxalone d. Fentanyl
D. Fentanyl
