Etomidate

Question 1

Etomidate (class)

Answer 1

sedative/hypnotic

Question 2

Etomidate (MOA)

Answer 2

rapid induction of anesthesia with minimal respiratory & cardiovascular effects

does not cause histamine release like other sedatives/hypnotics

Question 3

Etomidate (indications)

Answer 3

induction agent prior to paralytic in RSI

Question 4

Etomidate (dosage/route)

Answer 4

0.3mg/kg IVP (over 10 sec.) to a max of 20mg

may be repeated in 8-10 minutes

Question 5

Etomidate (side effects)

Answer 5

myoclonic skeletal muscle movement

hypotension

nausea & vomiting

apnea

Question 6

Etomidate (contraindications)

Answer 6

patients with known hypersensitivity

Question 7

Etomidate (special information)

Answer 7

may cause transient venous pain on injection

use with caution in patients with marked hypotension, severe asthma, or severe cardiovascular disease

Verapamil may interact to cause proloned respiratory depression & apnea

onset of action is 10-20 seconds & lasts 10 minutes

rapid injection can lead to hypotension

Question 8

Etomidate (pediatric note)

Answer 8

see pediatric drug guide