ET: Pregnancy Placenta Flashcards
Ovary during early pregnancy
Dominant follicle (breed mare within 48 hrs prior to OV)
After OV, 1 CL forms, later 2nd CLs form
Gestation length
Begins day of OV and ends with foaling (11-12 m)
Assessed by ultrasound or TRP
Transit time from ovary to uterus is…
5.5-6 days
Unfertilized ova (UFO)
Retained in the uterine tube
Uterotubal junction blocks UFO from entering the uterus
Significant events during gestation
Maternal recognition of pregnancy
Fixation of the embryonic vesicle / conceptus in the uterus
Attachment of early placenta to the endometrium
Placental maintenance
Transuterine migration (TUM)
Recognition of pregnancy results from successful TUM
Essential for yolk sac to notify the mare is pregnant
Day 16: day of fixation
When does Recognition of pregnancy occur?
Day 12-14
successful ROP measured by blocking PGF release from the endometrium
Primary CL
30 days of progest production
FSH release and follicular waves continue throughout pregnancy
Fetal trophoblasts form endometrial cups
Endometrial cups
Temporary structures, source of eCG/PMSG @ 34 days of gestation (pale, raised, ring formation)
Causes follicles on ovaries to luteinize
Secondary CLs
Second rise in progesterone
What happens after 40-45 days gestation with pregnancy loss?
Its hard to short-cycle her to bring her back into estrus as endometrial cups persist (delay for 3-4 months)
Placental attachment
Between 40-60 days of gestation
70-90 days gestion
Transition from ovarian to uterine/placental maintenance
No longer ovarian dependent
90 to 100+ days of gestation
Pregnancy maintenance uterine/ placental
Ovaries don’t maintain pregnancy
Chronic girdle
Pale, circular area around sphere (location of trophoblast cells)
@ 16 days, comes into contact with uterine horn