Endo - Thyroid Disease

Question 1

Clinical presentation of congenital hypothyroidism?

Answer 1

**prolonged neonatal jaundice

Poor feeding

Constipation **

Increased sleep, reduced activity,

**Hypotonia
Macroglossia
Umbilical hernia **

Question 2

What issues can undiagnosed hypothyroidism cause?

Answer 2

Neurodevelopment
Intellectual ability

This can be congenital or acquired

Question 3

What causes congenital hypothyroidism?

Answer 3

Child born with underactive thyroid gland, can be due to underdevelopment or a fully developed gland that does not produce enough hormones.

Question 4

What is acquired hypothyroidism?

Answer 4

child develops an underactive thyroid gland when previously it was functioning normally.

Question 5

What is the most common cause of acquired hypothyroidism?

Answer 5

autoimmune thyroiditis (hashimoto’s).

Question 6

Signs of congenital hypothyroidism

Answer 6

Hypotonia
Macroglossia
Umbilical hernia

Question 7

Signs of acquired hypothyroidism in a child?

Answer 7

Fatigue,
weight gain,
poor school
constipation
dry skin
hair loss

Question 8

Investigations?

Answer 8

TFTs
Thyroid US
Thyroid antibodies

Question 9

How is congenital hypothydoism picked up?

Answer 9

Screened for on newborn blood spot screening test

Question 10

How to manage hypothyrodism ?

Answer 10

Oral levothyroxine once daily

Question 11

Complications of thyroid disease?

Answer 11

Increased risk of other auto-immune conditions : T1DM, RA, Vitiligo