More infections

Question 1

What organism causes it?

HAND FOOT MOUTH

Answer 1

Coxsackie A16 virus

Severe version : Enterovirus 71

Question 2

Signs and symptoms

HAND FOOT MOUTH

Answer 2

Painful + itchy - vesicular lesions
hand foot mouth + tongue + bum

fever + sore throat + spots in mouth become ulcers

Question 3

Management

HAND FOOT MOUTH

Answer 3

Supportive to clear in 10 days

Question 4

What organism causes roseola infatum?

ROSEOLA INFANTUM / HHV6

Answer 4

HHV6

Question 5

What aged children does it affect

ROSEOLA INFANTUM / HHV6

Answer 5

Most kids have had infection by age 3 as is highly contagious

Question 6

Signs and symptoms

ROSEOLA INFANTUM / HHV6

Answer 6

High fever + malaise

Small pink spots = macular rash appearing as fever wanes

Question 7

Rash spread?

ROSEOLA INFANTUM / HHV6

Answer 7

Starts on neck / body and spread to arms

+ Nagayama spots : uvula and soft palate spots

Question 8

Differentials for Roseola infatum?

ROSEOLA INFANTUM / HHV6

Answer 8

Measles and rubella so need to get serology

Question 9

How to investigate children over 18 months

HIV

Answer 9

antibody detection via ELISA

Question 10

How to investigate in children under 18 months?

HIV

Answer 10

still have transplantal anti-HIV igG from mum

PCR of virus, measured at birth, 6 weeks, 12 weeks, 18 months

Question 11

Management at birth?

HIV

Answer 11

Urgent cord clamping and baby washed

ZIDOVUDINE monotherapy for 2-4 weeks
or
PEP combination if high risk

Mum does NOT breastfeed