Malabsorption

Question 1

What is coeliac disease?|

Answer 1

sensitivity to gluten.

Children normally present before the age of 3 years, following the introduction of cereals into the diet.

Question 2

What deficiency is seen in lactose intolerance?

Answer 2

lactose dehydrogenase

Can occur as a temporary thing secondary to gastroenteritis

Question 3

Clinical features of coeliac disease?

Answer 3

Failure to thrive (growth) when weaning begins

DIarrhoea

Abdo distension

Dermatitis herpetiformis

Question 4

What ix for coeliac disease?

Answer 4

Anti TTG antibodies

Anti-endomysial antibodies

• check for IgA deficiency before testing for antibodies

Question 5

What will be seen on endoscopy and intestinal biopsy?\

Answer 5

Villous atrophy

crypt hyperplasia

Question 6

What exclusiosn need to be made before coeliac is confirmed?

Answer 6

Exclude gastroenteritis (stool sample) and crohn’s (faecal calprotectin).

Question 7

How to manage coeliac disease?

Answer 7

• Gluten Free Diet → avoid wheat, rye and barley.
• Annual Review → check height, weight, and BMI.

Review symptoms and adherance to diet.

Question 8

What complications can occur in a child with coeliac disease?

Answer 8

vitamin deficiency, anaemia, osteoporosis, EATL.