emerging and remerging infections Flashcards
what is an emerging infectious disease ?
- is a disease caused by a newly discovered infectious agent or by a newly identified variant of a known pathogen
- for it to be emerging the incidence in humans must have increased in the last two decades
what is a re-emerging infection ?
a disease which was previously controlled but once again has risen to be a significant health problem.
what is the most common source of emerging infections?
zoonotic infections
what are the factors affecting the emerging and re-emerging diseases ?
- ecological changes and agricultural development
- changes inn human demographics and behaviour
- international travel and commerce
- microbial adaptation and change
- break down of public health measures
- intent to harm
- war and famine
how do ecological changes and agricultural development affect emerging and remerging infections ?
- influence waterborne, vector borne disease transmission
2. increases exposure to pets and wild animals
how do changes in human demographics and behaviour affect emerging remerging infections ?
- increase in population density
- increase in number of populations with weakened immunity
- higher risk behaviour : drug use and unprotected sex
how does international travel and commerce affect emerging and remerging infections ?
transport of livestock facilitates movements of viruses and arthropods
how does microbial adaptation and change affect emerging and remerging infections ?
- over prescription of antibiotics by doctors
- increased ab resistance
- increased virulence
- jumping species from animals to humans
how does the breakdown of public health measures affect emerging and remerging infections ?
- lack of basic hygiene
- inadequate vaccinations
- lack of monitoring and reporting
how does the intent to harm have an affect emerging and remerging infections ?
bioterrorism
bio crimes
how does war and famine have an effect on emerging and remerging infections ?
war refugees are forced onto new areas where they are exposed to new microbes from vectors and people
what is an epidemic ?
a disease that affects a large number of people within na community, population or a region
what is a pandemic ?
it an epidemic that is spread over multiple countries or continents
what is the difference between epidemics and endemics in terms of activity ?
- epidemic is actively spreading
2. endemic are a constant presence in a specific location
what is an outbreak ?
a greater than anticipated increase in the number of endemic cases
what is the WHO’s pandemic alert system ?
phase 1 to 6
phase 1 - low risk
phase 6 - a full pandemic
what does phase 1 of the WHO pandemic alert describe ?
a virus inn animals has caused no known infections in humans
what does phase 2 in the WHO pandemic alert system describe?
an animal virus has caused infections in humans
what does phase 3 in the WHOs pandemic alert system describe ?
there are small clusters of disease in humans, illness maybe spreading from human to human but not enough to be causing community level outbreaks
what does phase 4 in the WHOs pandemic alert system describe ?
the disease is spreading from person to person with confirmed outbreaks at the community level
what does phase 5 in the WHOs pandemic alert system describe ?
the disease is spreading between humans inn more than one country
what does phase 6 in the WHOs pandemic alert system describe ?
at least one more country, in a different region from phase 5, has community-level outbreaks.
what is an epidemic curve ?
shows the frequency of new cases over time based on the date of onset of disease
what are the three basic types of epidemic curves ?
- point source outbreaks
- continuous common source epidemics
- propagated epidemic
what does a point source outbreak curve describe ?
- involves a common source
- all the exposure tends to happen inn a brief time period
- rapid increase in cases followed by a slower decline all occurring in a single incubation period
what does a continuous common source epidemic describe ?
- implies that there is an ongoing source of contamination
2. lasts longer than a single incubation period
what does a propagated/ progressive source curve describe ?
shows one or more people infected inn the initial wave that infect another group who then become a second wave
successively larger peaks and each peak is separated by incubation periods
how can emerging infectious diseases be prevented ?
- surveillance and response
- applied research
- infrastructure and training
- prevention and control