emerging and remerging infections Flashcards

1
Q

what is an emerging infectious disease ?

A
  1. is a disease caused by a newly discovered infectious agent or by a newly identified variant of a known pathogen
  2. for it to be emerging the incidence in humans must have increased in the last two decades
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2
Q

what is a re-emerging infection ?

A

a disease which was previously controlled but once again has risen to be a significant health problem.

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3
Q

what is the most common source of emerging infections?

A

zoonotic infections

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4
Q

what are the factors affecting the emerging and re-emerging diseases ?

A
  1. ecological changes and agricultural development
  2. changes inn human demographics and behaviour
  3. international travel and commerce
  4. microbial adaptation and change
  5. break down of public health measures
  6. intent to harm
  7. war and famine
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5
Q

how do ecological changes and agricultural development affect emerging and remerging infections ?

A
  1. influence waterborne, vector borne disease transmission

2. increases exposure to pets and wild animals

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6
Q

how do changes in human demographics and behaviour affect emerging remerging infections ?

A
  1. increase in population density
  2. increase in number of populations with weakened immunity
  3. higher risk behaviour : drug use and unprotected sex
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7
Q

how does international travel and commerce affect emerging and remerging infections ?

A

transport of livestock facilitates movements of viruses and arthropods

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8
Q

how does microbial adaptation and change affect emerging and remerging infections ?

A
  1. over prescription of antibiotics by doctors
  2. increased ab resistance
  3. increased virulence
  4. jumping species from animals to humans
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9
Q

how does the breakdown of public health measures affect emerging and remerging infections ?

A
  1. lack of basic hygiene
  2. inadequate vaccinations
  3. lack of monitoring and reporting
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10
Q

how does the intent to harm have an affect emerging and remerging infections ?

A

bioterrorism

bio crimes

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11
Q

how does war and famine have an effect on emerging and remerging infections ?

A

war refugees are forced onto new areas where they are exposed to new microbes from vectors and people

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12
Q

what is an epidemic ?

A

a disease that affects a large number of people within na community, population or a region

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13
Q

what is a pandemic ?

A

it an epidemic that is spread over multiple countries or continents

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14
Q

what is the difference between epidemics and endemics in terms of activity ?

A
  1. epidemic is actively spreading

2. endemic are a constant presence in a specific location

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15
Q

what is an outbreak ?

A

a greater than anticipated increase in the number of endemic cases

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16
Q

what is the WHO’s pandemic alert system ?

A

phase 1 to 6
phase 1 - low risk
phase 6 - a full pandemic

17
Q

what does phase 1 of the WHO pandemic alert describe ?

A

a virus inn animals has caused no known infections in humans

18
Q

what does phase 2 in the WHO pandemic alert system describe?

A

an animal virus has caused infections in humans

19
Q

what does phase 3 in the WHOs pandemic alert system describe ?

A

there are small clusters of disease in humans, illness maybe spreading from human to human but not enough to be causing community level outbreaks

20
Q

what does phase 4 in the WHOs pandemic alert system describe ?

A

the disease is spreading from person to person with confirmed outbreaks at the community level

21
Q

what does phase 5 in the WHOs pandemic alert system describe ?

A

the disease is spreading between humans inn more than one country

22
Q

what does phase 6 in the WHOs pandemic alert system describe ?

A

at least one more country, in a different region from phase 5, has community-level outbreaks.

23
Q

what is an epidemic curve ?

A

shows the frequency of new cases over time based on the date of onset of disease

24
Q

what are the three basic types of epidemic curves ?

A
  1. point source outbreaks
  2. continuous common source epidemics
  3. propagated epidemic
25
Q

what does a point source outbreak curve describe ?

A
  1. involves a common source
  2. all the exposure tends to happen inn a brief time period
  3. rapid increase in cases followed by a slower decline all occurring in a single incubation period
26
Q

what does a continuous common source epidemic describe ?

A
  1. implies that there is an ongoing source of contamination

2. lasts longer than a single incubation period

27
Q

what does a propagated/ progressive source curve describe ?

A

shows one or more people infected inn the initial wave that infect another group who then become a second wave
successively larger peaks and each peak is separated by incubation periods

28
Q

how can emerging infectious diseases be prevented ?

A
  1. surveillance and response
  2. applied research
  3. infrastructure and training
  4. prevention and control