ECLAMPSIA Flashcards

1
Q

What is eclampsia

A

Elevated BP associated with proteinuria and convulsion

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2
Q

Nature of convulsion in eclampsia

A

Similar to epileptic fit, tonic and clonic phases followed by coma.
Fits are repetitive and last for short durations of 60-90 seconds

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2
Q

Obstetric complications of eclampsia

A

Foetal distress
Placental abruption

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2
Q

Symptoms

A

Fits
Unconsciousness

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2
Q

Treatment objectives in eclampsia

A

To protect the patient from injury
To prevent further fits
To lower the blood pressure
To monitor maternal and foetal complications
To prevent maternal mortality
To deliver the baby when the mother is stable

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2
Q

Investigations in eclampsia

A

FBC
Blood film for MPS
BUE
Urinalysis and culture
Ultrasound scan

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2
Q

Nonpharmacological management after the fits

A

Catheterise patient
Obtain IV access
Deliver foetus if mother is stable with no further fits

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3
Q

Initial non-pharmacological management of eclampsia

A

Lay patient in recovery position
Prevent patient from falling
Avoid restricting patient to prevent joint injury
Keeping patient NPO
Place patient in recovery position
Maintain airway
Artificial respiration during general anesthesia
Consider turning unconscious pospartum patients

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3
Q

How to maintain patient’s airway

A

Holding up chin if possible
or
Inserting mechanical airway to hold down the tongue

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3
Q

Purpose of ultrasound scan in eclampsia

A

to exclude multiple pregnancy
and/or molar pregnancy

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3
Q

Signs of eclampsia

A

Elevated BP
Proteinuria
Convulsions
Coma

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3
Q

Why do we avoid restricting patients with eclampsia

A

to prevent limb fractures and joint
dislocations

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3
Q

Why do we turn patients who are unconscious for extended periods

A

Prevent bed sores

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3
Q

Fluid replacement in eclampsia

A

Normal saline
Ringer’s lactae 1L/6hours max.

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3
Q

Maintenance dose for Mag. sulphate

A

IM 5g into alternating buttocks every 4 hours till 24 hours after last seizure or delivery

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3
Q

Protocol for pharmacological management of eclampsia

A

Fluid replacement
Treat convulsions
Treat recurrent convulsions and convulsions not responding to magnesium sulphate
Treat hyeprtension

3
Q

Factors affecting mode of delivery

A

Mother’s preference
Mother’s condition
Foetal condition

3
Q

Treatment of recurrent convulsions (fits>20mins after)

A

> 70kg: 4g of IV Mag. sulphate
<70kg: 2g of IV Mag. sulphate

3
Q

Treatment of HTN in eclampsa

A

IV hydralazine or IV Labetalol

3
Q

Monitoring parameters for mag. sulphate

A

Respiratory rate
Patellar reflex
Urine output

3
Q

Initial management of convulsions for Magnesium sulphate

A

4g IV Mag. sulphate (20ml of 20%) over 5-15mins
then
M Mag. sulphate (10ml of 50%), 5g into each buttock

3
Q

Management of magnesium sulphate toxicity

A

Assisted respiration

10ml of 10% Calcium gluconate IV inf. over 10 mins

3
Q

Treatment of convulsions not responding to mag. sulphate

A

IV Diazepam 10mg over 2-3mins (not exceeding 2.5mg/min)
then
<60kg: 5mg 8 hourly
>60kg: 5-10mg hourly
Maximum of 500mcg/kg in a day or 30mg in 24 hours

3
Q

Dosing for IV Hydralazine

A

5-10mg stat. over 5-10mins
then
Repeat every 20-30mins till BP is reduced
or
Hydralzine infusion 20-40mg in 500ml N/S, rate according to BP

3
Q

Labetalol dosing in hypertension in eclampsia

A

20mg stat. over at least 1 mins
then
repeat at 10 mins interval if BP>160/110 as follows 40mg, 80mg, 80mg to a cummulative max of 220mg.

when BP<160/110mmHg,
start infusion at 40mg/hr and double at 30mins intervals till a satisfactory reponse or to a max of 160mg/h