DYSLIPIDEMIA

Question 1

Primary target for Intervention in dyslipidemia

Answer 1

LDL

Question 2

Primary target for Intervention in dyslipidemia

Answer 2

LDL

Question 3

Since treatment for dyslipidemia is life long, there should be periodic monitoring of these parameters to forestall medication related side effects

Answer 3

Liver and muscle enzymes ( transaminases and creatine kinase)
Blood glucose

Question 4

Causes of dyslipidemia

Answer 4

High intake of saturated fats
Lack of physical activity
Metabolic syndrome
Hereditary factors
Excessive alcohol intake
Hypothyroidism
Neohrotic syndrome

Question 5

Causes of dyslipidemia

Answer 5

High intake of saturated fats
Lack of physical activity
Metabolic syndrome
Hereditary factors
Excessive alcohol intake
Hypothyroidism
Neohrotic syndrome

Question 6

Which form of dyslipidemia will present with abdominal pain

Answer 6

Hypertriglyceridemia due to pancreatitis

Question 7

Which form of dyslipidemia will present with abdominal pain

Answer 7

Hypertriglyceridemia due to pancreatitis

Question 8

Corneal arcus

Answer 8

Whitish rings around the cornea

Question 9

Xanthelasmata

Answer 9

Yellow skin eruptions around the eyes

Question 10

Lipaemic blood

Answer 10

Whitish blood sample

Question 11

Signs of dyslipidemia

Answer 11

Corneal arcus
Xanthelasmata
Lipaemic blood

Question 12

Investigations in dyslipidemia

Answer 12

Fasting lipid profile
Thyroid function test
Plasma protein
Urine protein

Question 13

Purpose of investigating plasma protein and urine protein in dyslipidemia

Answer 13

Exclude nephrotic syndrome

Question 14

When is it necessary to do a thyroid function test in dyslipidemia

Answer 14

When lipids are very high

Question 15

Treatment objectives in dyslipidemia

Answer 15

To reduce risk of ASCVD events and related deaths in healthy individuals and those who have suffered a CVD event

To reduce LDL-C to target

Question 16

LDL-C target in primary prevention individuals 21 years or older with untreated LDL of 4.9mmol/l or more

Answer 16

At least a 50% reduction

Question 17

LDL-C target for primary prevention in individuals 40 to 75 years either diabetes and an untreated LDL of 1.8 to 4.9mmol/L

Answer 17

30 to 49% reduction in LDL

Question 18

LDL target in secondary prevention

Answer 18

Less than 1.8mmol/L

Question 19

Non-pharmacological interventions in dyslipidemia

Answer 19

Dietary modifications
Weight reduction
Reduction in alcohol
Regular physical activity

Question 20

Dyslipidemia Pharmacological treatment: Low CVD - primary prevention

Answer 20

Simvastatin 10 to 20mg daily

Question 21

Dyslipidemia pharmacological management
Moderate CV risk (diabetes and CVD risk equivalent)

Answer 21

Atorvastatin 10-20mg daily
Or
Rosuvastatin 5-10mg daily
Or
Simvastatin 20-40mg daily

Question 22

Dyslipidemia pharmacological management
Moderate CV risk (diabetes and CVD risk equivalent)

Answer 22

Atorvastatin 10-20mg daily
Or
Rosuvastatin 5-10mg daily
Or
Simvastatin 20-40mg daily

Question 23

Dyslipidemia management in high CVD risk patients eg: secondary prevention

Answer 23

Atorvastatin 40-80mg daily
Or
Rosuvastatin 20-40mg daily

Question 24

Referral criteria for dyslipidemia

Answer 24

Patient who remains outside target values despite adequate dietary, exercise and medication therapy