DNA Replication Flashcards
When does DNA replication occur?
Interphase
What does DNA replication produce?
Two exact replicas of the DNA model
What does the new DNA molecules look like?
Each new chromosome consists of two identical chromatids and are attached at the centromere
What bonds hold nucleotides together?
Hydrogen
What is the role of helicase?
Unwinds and unzips DNA
What are the SSBP for?
To stop the strands from joining and from folding over one another
How many template strands are there
2
What does RNA primase do?
Synthesises RNA primers that are complementary to the DNA template
What is the role of DNA polymerase III?
Catalyses the addition of free nucleotides complementary to the template.
What direction do new strands HAVE to be made in ?
5-3
What is the leading strand?
The Strand of DNA in which runs 5-3
What is the lagging strand?
The strand of DNA which runs 3-5
What happens with the lagging strand?
It must be built backwards from the position of the RNA primer. These short fragments are known as Okazaki fragments
What is the role of DNA polymerase I?
To remove RNA primers and replace them with DNA
What is the role of ligase?
Joins neighbouring fragments together