Diseases of the Aorta Flashcards

1
Q

Tunica intima

A

layer of endothelial cells

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2
Q

tunica intima is separated from the tunica media by the

A

internal elastic lamina

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3
Q

Tunica media is separated from the tunica adventitia by the

A

external elastic lamina

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4
Q

Tunica media

A

smooth muscle cells

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5
Q

tunica adventitia

A

thin connective tissue layer

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6
Q

Atherosclerosis risk factors

A

hypertension

hypercholesterolaemia

smoking

diabetes

family history

male

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7
Q

Atherosclerosis can lead to..

A

stroke

myocardial infarction

aneurysm

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8
Q

Aneurysm definition

A

a localised enlargement of an artery caused by the weakening of the vessel wall

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9
Q

True aneurysm

A

weakness and dilation of wall

involves all 3 layers

atherosclerosis/hypertension etc

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10
Q

False aneurysm

A

rupture of the wall of the aorta with the haemotoma either contained within the tunica adventitia or the surrounding soft tissue

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11
Q

signs and symptoms of thoracic aneurysms

A

asymptomatic
(based on location)

SOB

hoarseness

chest pain

hypotension

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12
Q

Aortic dissection

A

tear in the inner wall of the aorta

blood forces the walls apart

medical/surgical emergency

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13
Q

Dissection aetiology

A

hypertension

atherosclerosis

trauma

Marfan’s Syndrome

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14
Q

Aortic dissection histology

A

cystic medial necrosis

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15
Q

Symptoms of aortic dissection

A

tearing

severe chest pain

collapse

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16
Q

Aortic dissection examination

A

reduce or absent peripheral pulses

hypo or hypertension

pulmonary oedema

widened mediastinum

17
Q

Aortic dissection investigations

A

CXR

ECho

CT scan

18
Q

aortic dissection treatment

A

surgery

BP control

Sodium nitroprusside

beta blocker

19
Q

Takayasu’s Arteritis

A

Granulomatous vasculitis

aorta and main branches

stenosis, thrombosis, aneurysms, renal artery stenosis

20
Q

Takayasu’s arteritis treatment

A

steroids

surgery

21
Q

Syphilis

A

STD

Treponema pallidum

22
Q

Syphilis treatment of late stages

A

antibiotics

23
Q

Tertiary syphilis can lead to

A

shyphilitic aortitis - aneurysm

aortic regurgitation

24
Q

Congenital aortic aneurysm can present as

A

bicuspid aortic valve

coarctation

marfans syndrome

25
Q

Bicuspid aortic valve is the most common congenital abnormality. it is prone to..

A

aneurysm and dissection

26
Q

Coarctation is the

A

aortic narrowing close to where ductule arterioles inserts

27
Q

3 types of coarctation

A

pre-ductal

ductal

post-ductal

28
Q

Signs of coarctation

A

cold legs

poor leg pulses

29
Q

Symptoms of coarctations

A

infancy - heart failure and failure to thrive

later life - hypertension