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Infectieziekten 3 > Diagnostiek > Flashcards

Diagnostiek Flashcards

1
Q

What are the steps in the diagnostic process?

A

Pt → order dr → collectie → transport → analyse + labokwaliteitscontrole → data flow → interpretatie dr → diagnose en behandeling

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2
Q

What is the first phase of the diagnostic process?

A

Pre-analytische fase

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3
Q

What is included in the pre-analytical phase?

A

Staal collectie, collectie relevante medische informatie, voorbereiding, transport en bewering van staal tot in labo geraken

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4
Q

What is the second phase of the diagnostic process?

A

Analytische fase

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5
Q

What is the third phase of the diagnostic process?

A

Post-analytische fase

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6
Q

What defines Category 1 samples?

A

Normaal steriel, zoals bloedkweek, CSF, biopsie

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7
Q

In Category 1 samples, is the presence of any germ relevant?

A

Ja

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8
Q

What defines Category 2 samples?

A

Niet aspectisch kunnen afnemen → nooit volledig steriel, zoals urine, respiratoire tractus

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9
Q

In Category 2 samples, what is important to note?

A

Overwegende kiem + hoort bij pathogene klasse

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10
Q

What defines Category 3 samples?

A

Zwaar gekoloniseerd, zoals huid, mucosa, stoelgang, keel

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11
Q

In Category 3 samples, is the presence of many germs relevant?

A

Ja (veel)

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12
Q

What is the advantage of microscopy and Gram staining?

A

Kwaliteitscontrole, snelle diagnostische informatie, onderscheid gram + of -

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13
Q

What is a disadvantage of microscopy and Gram staining?

A

Lage sensitiviteit, lage discriminatie kracht

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14
Q

What is a key benefit of bacteriële kweek en identificatie?

A

Detectie verschillende bacteriën op hetzelfde moment

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15
Q

What is a disadvantage of bacteriële kweek?

A

Sommige zeer traag, zoals TB

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16
Q

What is an advantage of virale kweek?

A

Detectie verschillende virussen, gevoeligheidstesten mogelijk

17
Q

What is a disadvantage of virale kweek?

A

Soms late diagnose door traag groeiende virussen

18
Q

What is an advantage of antigen tests (including ELISA)?

A

Snel testresultaat, gemakkelijk om uit te voeren

19
Q

What is a disadvantage of antigen tests?

A

Sensitiviteit afhankelijk van lading

20
Q

What is a key benefit of moleculaire technieken?

A

Hoge sensitiviteit en specificiteit

21
Q

What is a disadvantage of moleculaire technieken?

A

Alleen vinden waarnaar gezocht wordt

22
Q

What is a major advantage of serologie?

A

Gebruik voor niet-kweekbare micro-organismes

23
Q

What is a disadvantage of serologie?

A

Specificiteit niet altijd geweldig

24
Q

What is the rationale behind diagnostic stewardship?

A

Juiste test, voor juiste pt op het juiste tijdstip voor optimale klinische zorg

25
Q

What does post-test probabiliteitscalculatie involve?

A

In theorie performantie test

26
Q

True or False: Testing should be done on patients with the lowest pre-test probability.

A

False

27
Q

What is a strategy to improve diagnostic testing?

A

Restrictie pt met lage pretest probabiliteit

28
Q

What is a disadvantage of combination testing?

A

Suboptimale sensitiviteit

29
Q

What is a disadvantage of molecular panel-based testing?

A

Supaoptimale specificiteit

30
Q

What is a key factor for effective diagnostic testing in pneumonia?

A

Gevoeligheidsbepalling nodig

Infectieziekten 3 (8 decks)

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