Development of head and neck Flashcards

1
Q

In week 4, what proportion of the embryo is made up of the future head and neck?

A

Half of it

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2
Q

What is the structure of the face of the embryo at week 4 of development?

A

No structure, completely undeveloped

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3
Q

What is the structure of the head and neck of the embryo in early development?

A

Frontonasal prominence in the head

Pharyngeal arches

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4
Q

Why is the frontonasal prominence named so?

A

At the front of the embryo

Where nose develops

Prominent because of developing brain behind it

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5
Q

How many pharyngeal arches are there in the embryo in early development?

A

5 of them

but are numbered 1, 2, 3, 4, 6

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6
Q

What is a pharyngeal arch made up of?

A

Mesenchymal proliferation
-mesoderm with some neural crest cells

Inner endoderm lining
Outer ectoderm lining

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7
Q

What does the mesenchyme in the pharyngeal arch develop into?

A

Cartilage bar

Muscle

Artery

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8
Q

What supplies a pharyngeal arch?

A

Each pharyngeal arch has its own blood supply

and is innervated by its own cranial nerve

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9
Q

Which pharyngeal arch is the biggest?

A

1st pharyngeal arch

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10
Q

How do the pharyngeal arches change in size?

A

Get smaller from the 1st pharyngeal arch to the 6th pharyngeal arch

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11
Q

How does the number of derivatives of the pharyngeal arches change? Why?

A

Fewer derivatives from the 1st pharyngeal arch to the 6th pharyngeal arch
because they get smaller

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12
Q

What are the parts of the 1st pharyngeal arch?

A

Maxillary zone

Mandibular zone

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13
Q

Which cranial nerves innervate the pharyngeal arches?

A

CNs 5, 7, 9, 10

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14
Q

Which cranial nerve innervates the 1st pharyngeal arch?

A

CN5 trigeminal nerve

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15
Q

Which cranial nerve innervates the 2nd pharyngeal arch?

A

CN7 facial nerve

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16
Q

Which cranial nerve innervates the 3rd pharyngeal arch?

A

CN9 glossopharyngeal nerve

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17
Q

Which cranial nerve innervates the 4th pharyngeal arch?

A

CN10 vagus nerve

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18
Q

Which cranial nerve innervates the 6th pharyngeal arch?

A

CN10 vagus nerve

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19
Q

Which muscles does the 1st pharyngeal arch give rise to?

A

Muscles of mastication

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20
Q

Which muscles does the 2nd pharyngeal arch give rise to?

A

Muscles of facial expression

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21
Q

Which muscles does the 3rd pharyngeal arch give rise to?

A

Stylopharyngeus

22
Q

Which muscles does the 4th pharyngeal arch give rise to?

A

Pharyngeal muscles

23
Q

Which muscles does the 6th pharyngeal arch give rise to?

A

Laryngeal muscles

24
Q

What is the cartilage bar of the 1st pharyngeal arch called?

A

Meckel’s cartilage

25
What bones does Meckel's cartilage develop into?
Malleus, incus Template for mandible
26
What is the cartilage bar of the 2nd pharyngeal arch called?
Reichert's cartilage
27
What bones does Riechert's cartilage develop into?
Stapes Upper part of hyoid bone Styloid process
28
What bones does the cartilage bar of the 3rd pharyngeal arch develop into?
Rest of hyoid bone
29
What does the cartilage bar of the 4th pharyngeal arch develop into?
Larynx cartilages - thyroid - cricoid - aretynoid
30
What does the cartilage bar of the 6th pharyngeal arch develop into?
Larynx cartilages - thyroid - cricoid - aretynoid
31
What is the blood supply of the 3rd pharyngeal arch?
Internal carotid artery
32
What is the blood supply of the 4th pharyngeal arch?
Left side gives aortic arch Right side gives brachiocephalic trunk
33
What is the blood supply of the 6th pharyngeal arch?
Pulmonary trunk
34
What happens to the blood supply of the 1st and 2nd pharyngeal arches?
Disappear
35
What is the name of the dent between pharyngeal arches in the endoderm?
Pharyngeal pouch
36
What do the pharyngeal pouches develop into?
Glands of head and neck
37
Which pharyngeal pouch is the biggest?
1st pharyngeal pouch | between the 1st and 2nd pharyngeal arches
38
What does the 1st pharyngeal pouch develop into?
Eustachian tube Middle ear
39
What does the second pharyngeal pouch develop into?
Palatine tonsils
40
What do the third and fourth pharyngeal pouches develop into?
Third - inferior parathyroid gland, thymus gland Fourth - superior parathyroid gland
42
What is the name of the dent between pharyngeal arches in the ectoderm?
Pharyngeal cleft
43
What does the 1st pharyngeal cleft develop into?
External acoustic meatus
44
What happens to the 2nd-6th pharyngeal clefts?
2nd pharyngeal cleft grows larger and downwards to cover and close up all the other clefts
45
What is a branchial cyst?
Fluid-filled sac in the neck
46
What is a branchial fistula?
Opening into neck
47
How do branchial cysts present?
Swelling in neck
48
Where are branchial cysts and fistulas located in the neck?
Anterior to the sternocleidomastoid muscle
49
Where are pharyngeal arches located in the embryo?
Lateral walls of pharynx
50
How does the development of the blood supply of the head and neck relate to the recurrent laryngeal nerve?
Explains why the right one turns under the right subclavian and why the left one turns under the aortic arch
51
How do branchial fistulas form?
2nd arch pharyngeal cleft grew larger and donwards but didn't fully cover all the other clefts gives opening into neck
52
How do branchial cysts form?
2nd pharyngeal cleft grew larger and downwards to cover all the other clefts but didn't fully close them up