Demyelination Flashcards

1
Q

What is the role of the myelin?

A
  1. Covers and protects the neuron
  2. Relay signals
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2
Q

What is the most common cause of damage to the myelin?

A

Autoimmune condition

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3
Q

What happens if the myelin is damaged?

A
  1. risk for meningitis
  2. delayed relay of impulses
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4
Q

What occurs if the myelin in the CNS is damaged?

A

Multiple Sclerosis

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5
Q

What occurs if the myelin in the PNS is damaged?

A

Guillain Barre Syndrome

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6
Q

In what population is Multiple Sclerosis more common in?

A

Women, 20-40 years old

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7
Q

How does Multiple Sclerosis start?

A

Starts as a viral infection then develops to an autoimmune condition

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8
Q

What are sclerosis?

A

Plaques or scar tissue

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9
Q

How does multiple sclerosis affect the eyes?

A
  1. Nystagmus
  2. Diplopia
  3. Scotoma
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10
Q

How does multiple sclerosis affect the neck?

A

Dysphagia

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11
Q

How does multiple sclerosis affect the chest?

A
  1. Respiratory depression
  2. Cardiac depression
  3. Cardiac arrythmias
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12
Q

How does multiple sclerosis affect the abdomen?

A

Bowel and bladder incontinence

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13
Q

How does multiple sclerosis affect the legs?

A

Ataxia (clumsy movements, loss of balance)

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14
Q

What is the Hallmark Manifestation of Multiple Sclerosis?

A

Charcot’s Triad

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15
Q

What are the symptoms in Charcot’s Triad?

A
  1. Scanning speech
  2. Intentional tremors
  3. Nystagmus
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16
Q

How is multiple sclerosis diagnosed?

A

MRI

17
Q

How is multiple sclerosis managed?

A
  1. Steroids
    - hydrocortisone
    - betamethasone
    - dexamethasone
  2. Muscle relaxants
    - Baclofen
    - Flexemil
  3. Assistive devices
  4. Bronchodilators
  5. Avoid hot baths
18
Q

In what population is Guillain Barre Syndrome common in?

A

Both men and women, 30-50 years old

19
Q

What causes Guillain Barre Syndrome?

A

Autoimmune condition and infectioon

20
Q

What bacteria is responsible for Guillain Barre Syndrome?

A

Camoylobacter jejuni

21
Q
A