Demyelination Flashcards
What is the role of the myelin?
- Covers and protects the neuron
- Relay signals
What is the most common cause of damage to the myelin?
Autoimmune condition
What happens if the myelin is damaged?
- risk for meningitis
- delayed relay of impulses
What occurs if the myelin in the CNS is damaged?
Multiple Sclerosis
What occurs if the myelin in the PNS is damaged?
Guillain Barre Syndrome
In what population is Multiple Sclerosis more common in?
Women, 20-40 years old
How does Multiple Sclerosis start?
Starts as a viral infection then develops to an autoimmune condition
What are sclerosis?
Plaques or scar tissue
How does multiple sclerosis affect the eyes?
- Nystagmus
- Diplopia
- Scotoma
How does multiple sclerosis affect the neck?
Dysphagia
How does multiple sclerosis affect the chest?
- Respiratory depression
- Cardiac depression
- Cardiac arrythmias
How does multiple sclerosis affect the abdomen?
Bowel and bladder incontinence
How does multiple sclerosis affect the legs?
Ataxia (clumsy movements, loss of balance)
What is the Hallmark Manifestation of Multiple Sclerosis?
Charcot’s Triad
What are the symptoms in Charcot’s Triad?
- Scanning speech
- Intentional tremors
- Nystagmus
How is multiple sclerosis diagnosed?
MRI
How is multiple sclerosis managed?
- Steroids
- hydrocortisone
- betamethasone
- dexamethasone - Muscle relaxants
- Baclofen
- Flexemil - Assistive devices
- Bronchodilators
- Avoid hot baths
In what population is Guillain Barre Syndrome common in?
Both men and women, 30-50 years old
What causes Guillain Barre Syndrome?
Autoimmune condition and infectioon
What bacteria is responsible for Guillain Barre Syndrome?
Camoylobacter jejuni
