Addison's and Cushing's and Pheochromocytoma Flashcards
What is the inner layer of the adrenal gland?
Medulla
What is the outer layer of the adrenal gland?
Cortex
What does the adrenal cortex release?
Glucocorticoids, Mineralocorticoids, Androgenic hormones
What does the adrenal medulla release?
Catecholamines
-Epinephrine (heart rate and respiratory rate)
-Norepinehrine (blood pressure)
What are examples of the different steroids in the adrenal cortex?
- Cortisol (stress hormone) and glucose
- Aldosterone
- Estrogen and testosterone
What is the cause of Addison’s disease?
- Hypofunctional adrenal gland
- Autoimmune condition
What are the manifestations of Addison’s in terms of hormones?
Low sugar, salt, androgen, and norepi but high epi
What are the manifestations of low sugar?
- Inability to tolerate stress (cortisol)
- hypoglycemia
- Inability to produce melanin stimulating hormone
What is a common symptoms of Addison’s patients in terms of skin?
Bronze skin
What are the manifestations of low salt?
- Fluid Volume Deficit
- Hyonatremia and Hyerkalemia
- Altered LOC
- Seizure
What are the manifestations of low androgens?
Poor amount of axillary/pubic hair
What is the manifestation of low norepinephrine?
Hypotension
Why does the epinephrine increase instead of decrease?
Acts as a compensatory mechanism
What are the manifestations of Addisonian Crisis?
Tachycardia, tachypnea, hypotension
What is the management of Addisons?
- Reduce stress
- High sodium low potassium diet