Comp Med No. 6 2011 Flashcards
Which type of PCR is used because it employs enzymes with 3’-5’ exonuclease activity to decrease errors?
a. Multiplex-PCR
b. Asymmetric PCR
c. Nested PCR
d. Hot-start PCR
e. High-fidelity PCR
e. High-fidelity PCR
To which taxonomic order does Myobia musculi belong?
a. Metastigmata
b. Mesostigmata
c. Prostigmata
d. Astigmata
c. Prostigmata
Which nucleotide sequence in the ribosomal gene complex was not conserved among divergent taxa of mites?
a. 5.8S rRNA
b. 18S rRNA
c. ITS1
d. ITS2
e. 28S rRNA
a. 5.8S rRNA
Establishment of endpoint criteria should be determined by which of the following?
a. Lack of impact on scientific integrity
b. Specific experimental model
c. Objective applicability
d. All of the above
e. None of the above
d. All of the above
One method used to determine the endpoint criteria to be used was consistently better when applied in the models analyzed by these authors than the other methods.
a. T
b. F
b. F
Experimental endpoints should be based upon which of the following considerations?
a. Humane
b. Scientific and legal
c. Ethical and practical
d. All of the above
e. None of the above
d. All of the above
- Digital geometry processing is used to generate a three-dimensional image of the inside of an object from a large series of two-dimensional X-ray images taken around a single axis of rotation best describes which of the following imaging modalities:
a. Ultrasound
b. CT scanning
c. PET scanning
d. MRI
b. CT scanning
Radiation of what type is indirectly emitted by a radionuclide tracer and detected to form images in PET scans?
a. Alpha particles
b. Beta particles
c. Gamma waves
d. X-rays
c. Gamma waves
Foxn1nu mice like the ones used in this study lack what type of immune cell?
a. B lymphocytes
b. T lymphocytes
c. NK cells
d. Neutrophils
e. All of the above
b. T lymphocytes
- Which of the following is associated with retained fetal membranes in C57Bl/6 mice?
a. Housing in individually ventilated cages
b. Housing near the top of the rack
c. Housing in static caging
d. Lower light levels
e. All of the above
a. Housing in individually ventilated cages
- The condition depicted below is associated with which?
a. Housing in individually ventilated cages
b. Stress leukogram
c. Decreased hematocrit
d. Housing near the bottom of the rack
e. All of the above
e. All of the above
T/F: Although jackets provide protection from self-injurious behavior, they still require frequent monitoring to prevent animal health problems.
True
T/F: TMJ luxation is common in laboratory settings.
False, TMJ luxation is uncommon.
T/F: Rats that luxate their TMJ rarely present with obvious clinical signs.
False, rats (and most animals) have significant and clear clinical abnormalities that can include inability to close mouth, inability to eat, and distress.
The leptin:adiponectin ratio is (increased/decreased) in animals with a body fat %>40.
increased
- Socially stressed African green monkeys get thinner. T/F
true
Give two serum biochemical markers predictive of risk of T2DM when elevated.
HbA1c, fructosamine
Adiponectin is released from what kind of tissue?
a. Pituitary
b. Brown fat
c. White fat
d. Hypothalamus
c. White fat
True or False: Sooty managabeys are a natural host of Simian Immunodeficiency Virus, which has been implicated in the origin of HIV2.
True
Which of the following has been associated with an increased risk of gastric cancer in humans?
a. H. pylori
b. Nitrosamines
c. Genetic predisposition
d. All of the above.
d. All of the above.
True or False: This is the first report of spontaneous gastric carcinoma in the Sooty Mangabey.
True
What unusual rodent has been used as an animal model for Zollinger-Ellison syndrome and is susceptible to spontaneous gastric carcinoid?
Mastomys natalensis (Multimammate Rat)
How is a “true aneurysm” defined in comparison to a “false aneurysm”?
A “true aneurysm” involves all layers of the arterial wall. False ones are hematomas form outside the artery due to a leak in the vessel.
Paraffin embedded tissues can be used for PCR testing ( T/ F)
True
Mycotic aneurysms are specifically caused by fungi (T/F)
F - This name describes both fungal and bacterial aneurysms.
Out of all aneurysms in humans, fungal causes are more common. (T/F)
False
In which of the following nonhuman primates have SRVD been identified?
a. M. Nemestrina, M. mulatta, M. arctoides, M. fascicularis
b. M. Nemestrina, M.mulatta, M. nigra, M. fascicularis
c. M.mulatta, M. arctoides, M. fascicularis. M. nigra
b. M. Nemestrina, M.mulatta, M. nigra, M. fascicularis
T or F: Simian Retrovirus type D2 is a single stranded RNA alpha retrovirus in the family retroviridae?
False: beta retrovirus
Fill in the blank: SRV/D2 is most frequently associated with _______________ while SRV/D1 is more often associated with infection characterized by __________________?
Retroperitoneal Fibromatosis, Subcutaneous Fibromatosis
T/F: The Papilla of Vater is found at the opening of the pancreatic and common bile ducts.
True
Which of these are reportedly the two most common neoplasias found in baboons?
a. Lymphosarcoma
b. Squamous cell carcinoma
c. Adenocarcinoma
d. Melanoma
a. Lymphosarcoma
&
c. Adenocarcinoma
Studies have shown that a tracheal cuff pressure greater than ___ mmHg may cause ischemia and possible ulceration/chondritis of the tracheal rings?
a. 15
b. 20
c. 30
d. 40
c. 30
T/F: Primary tracheal tumors are common in animals.
False
