Chp 5: Integumentary System Flashcards
Functions of Integumentary System
- Protection of internal organs from physical, chemical and microbial agents
- Body temperature regulation
- Synthesis of Vit D
- Cutaneous sensation: Helps body sense changes in environment (and respond)
- Blood reservoir
- Excretion of nitrogen containing wastes, water, and salt
Layers of the Epidermis: deep to superficial
stratum basale stratum spinosum stratum granulosum stratum lucidum (not present in thin skin) stratum corneum
Epidermis
Keratinized stratified squamous epithelium consisting of 4 distinct cell types and 4 or 5 layers
Fast turn-over, resists damage, offers protection
Keratinocytes
Produce keratin (fibrous protein) By the time they reach the skin surface, they are dead, scale-like structures. Millions rub off every day, new epidermis every 25-45 days. Persistent friction causes thickening of epidermis (callus)
Melanocytes
Spider shaped epithelial cells found only in stratum basale
Synthesize melanin
Langerhans cells
Star shaped dendritic cells arise from bone marrow, migrate to epidermis
ingest foreign substances and activate immune system
Tactile Cells (Merkel Cells)
Present at epidermal-dermal junction (in stratum basale); shaped like spiky hemisphere
Stratum basale
Deepest epidermal layer, aka stratum germinativum
Stratum spinosum
“prickly layer”
Stratum Granulosum
4-6 layers
Where process of keratinization begins
Stratum Lucidum
In thick skin only
Thin translucent band just above stratum granulosum
2-3 rows of clear, flat, dead keratinocytes
Stratum corneum (horny layer)
Outermost epidermal layer, 20-30 layers thick
4 Major cell types of epidermis: Keratinocytes
Produce keratin, give epidermis protective properties
Present in every layer of epidermis
4 Major cell types of epidermis: Melanocytes
Spider shaped cells that synthesize melanin
Found in deepest layer (stratum basale)
4 Major cell types of epidermis: Dendritic cells (Langerhans cell)
Star shaped dendritic cell
Ingests foreign substances, activates immune system
Found in stratum spinosum
4 Major cell types of epidermis: Merkel Cells (tactile cells)
Shaped like spiky hemisphere
Works with disclike sensory nerve ending to function as touch receptor
Thin Skin
Hairy, covers all body regions except palms and palmar surfaces of digits and soles
Fewer sudoiferous glands, sparser sensory receptors