Chp 16: Endocrine Flashcards
What is a gland?
An organ in an animal’s body that synthesizes a substance for release
Exocrine vs endocrine glands
Exocrine (with ducts): secretes products into cavities inside the body or its outer surface
Endocrine (without ducts): secretes hormones, no duct, transports through bloodstream
Hormones
Hormones are long distance chemical messengers released in one part of the body that travel in the blood and alter activities of cells in a different part of the body
Cell responses to hormone stimulation
Involve changes in membrane permeability, enzyme synthesis, activation, or inhibition, secretory activity, mitosis
Autocrines
short distane signal
chemicals that exert their effects on the same cells that secrete them ex// prostaglandins
Paracrines
short distance signal Act locally (within same tissue) but affect cell types other than those releasing the paracrine chemicals ex// somatostatin released by one population of pancreatic cells inhibits release of insulin by a different population of pancreatic cells
Neuroendocrine organ
Hypothalamus (has neural functions, produces and releases hormones)
Endocrine organs
Pituitary, thyroid, parathyroid, adrenal, pineal, pancreas, gonads, placenta
Organs that are not endocrine organs but secrete hormones
Adipose cells, thymus, small intestine, stomach, kidneys, heart, liver, skin
Hypothalamus and pituitary relationship
Action potentials travel down axons of hypothalamic neurons, causing hormone release from their axon terminals in posterior pituitary
Hypothalamic hormones released into hypophyseal portal system control release of anterior pituitary hormones
“master endocrine gland”
anterior pituitary is called the “master endocrine gland” b/c many of the numerous hormones it produces regulate the activity of other endocrine glands (though hypothalamus really controls activity of anterior pituitary)
Anterior Pituitary hormones
Growth hormone Thyroid stimulating hormone adrenocorticotropic hormone follicle stimulating hormone leuteinizing hormone prolactin
Hormone that stimulates ovulation in females and sperm production in males? (source?)
Follicle stimulating hormone
source: anterior pituitary
Glands that regulate body’s calcium homeostasis
Thyroid (calcitonin) and parathyroid (parathyroid hormone)
Pineal gland
Hangs from roof of third ventricle in diencephalon
Releases melatonin, important for “biological clock”