CHp 17 blood Flashcards
Why is blood is considered a connective tissue
(1) embryologically, it has the same origin (mesodermal) as do the other connective tissue types and (2) blood connects the body systems together bringing the needed oxygen, nutrients, hormones and other signaling molecules, and removing the wastes
Functions of blood
Transports respiratory gases, nutrients, hormones
Protects against foreign invading microbes
Helps regulate body temp
Prevents loss of excess blood (by clotting)
Blood characteristics
Sticky, opaque fliud
Scarlet (oxygen rich) to dark red (oxygen poor)
More dense and viscous than water
slightly alkaline (pH 7.35-7.45)
Components of blood
Plasma 55% of whole blood, least dense
Buffy coat <1% of whole blood, leukocytes and platelets
Erythrocytes 45% of whole blood (hematocrit) most dense component
Formed elements
Platelets 250,000-400,000
WBCs 5,000-9,000
RBCs 4.2 million - 6.2 million
Average blood mass
volume males v females
8% body mass
Males: 5-6 liters
Females 4-5 liters
Hematopoiesis
blood production
begins in early embryo (yolk sac); liver and spleen
after birth all blood cells originate in bone marrow
Red Blood Cells
Biconcave, anucleate disc, salmon colored, 7-8 µm
“bags of hemoglobin”
Small size and biconcave shape provide huge surface area to volume; suitable for gas exchange
Lack mitochondria and generate ATP by anaerobic mechanisms, do not consume any of the oxygen they carry, making them very efficient O2 transporters
RBC lifespan
100-120 days; unable to synthesize new proteins, grow, or divide
Lose flexibility, become rigid and fragile, hemoglobin degenerates
Granulocytes
Neutrophils, eosinophils, basophils
Agranulocytes
Lymphocytes, monocytes
Which WBCs are most numerous? Least?
Never Let Monkeys Eat Bananas
neutrophils are most numerous, lymphocytes, monocytes, eosinophils, basophils
Which WBC will increase during allergic reaction?
Eosinophils and basophils
Which WBC will increase during parasitic infections?
Eosinophils
Platelets
Fragments of megakaryocytes
Essential for blood clotting, form temporary plug that seals break in blood vessel lining