Chp 12: Central Nervous System Flashcards
Main regions of adult brain
Cerebrum: cerebral hemispheres (cortex, white matter, basal nuclei)
Diencephalon (thalamus, hypothalamus, epithalamus) retina
Brain stem: midbrain, pons, medulla oblongata
Cerebellum
Adult neural canal regions (ventricles)
Lateral ventricles, third ventricle, cerebral aqueduct, fourth ventricle, central canal
Major lobes of cerebrum
Frontal lobe (1) Parietal lobes (2) Temporal lobes (2) Occipital lobes (1) insula
Gyrus/gyri
Elevated ridges of tissue
Sulcus/sulci
Shallow grooves
Fissures
Deeper grooves that separate large regions of brain
Median longitudinal fissure
separates the 2 cerebral hemispheres
Transverse cerebral fissure
separates cerebral hemispheres from cerebellum below
Lateralization of hemisphere function
Each hemiphere of the brain has abilities not completely shared by its partner
Sylvian/Lateral fissure
Separates frontal and parietal lobes from temoral lobe
Cerebrum
83% of brain mass
2 hemispheres connected by corpus callosum
1. superficial cortex of gray matter
2. internal white matter
3. basal nuclei (islands of gray matter, deep within white matter)
Cerebral cortex
outermost layer of gray matter
makes up superficial aspect + functional areas of the cerebrum, contains 70% of the neurons of CNS
Functional areas of cerebral cortex
Motor, sensory, association
Functional areas of cerebral cortex: motor
control voluntary movement
precise, skilled voluntary movements
Functional areas of cerebral cortex: sensory areas
conscious awareness of sensation
Functional areas of cerebral cortex: association areas
integrate diverse information
Cerebral white matter: Commissures/commissural fibers
connect corresponding gray areas of the two hemispheres, allow 2 hemispheres to function as coordinated whole
Largest commissure is corpus callosum
Cerebral white matter: Association fibers
connect different parts of the same hemisphere
connect adjacent gyri or connect different cortical lobes
Cerebral white matter: Projection fibers
Tie cortex to rest of the nervous system and to the body’s receptors and effectors
Run vertically
Basal nuclei (basal ganglia)
Collection of nuclei deep to white matter of cerebral cortex
Control autonomic movements of skeletal muscles and help regulate muscle tone
caudate nucleus, globus pallidus,putamen
Diencephalon
paired structure, between brain stem and cerebral hemispheres
Thalamus, hypothalamus, epithalamus
Thalamus
part of diencephalon
central relay station of all sensory impulses except olfactory senses to cortex
Hypothalamus
part of diencephalon
controls autonomic functions, produces hormones, regulates body temperature, thirst, hunger, swallowing reflexes, pituitary secretions
Epithalamus
part of diencephalon
has pineal body, regulates circadian rhythm
Brain stem
midbrain, pons, medulla oblongata
Brain stem: midbrain
“bridge”
pons to diencephalon
motor impulses from cerebrum to cerebellum and spinal cord
superior colliculus: visual, auditory, somatosensory stimuli
inferior colliculus: processing auditory info
cerebral peduncles: clusters of motor and sensory fibers
substantia nigra: helps control subconscious muscle activity
Brain stem: pons
Somatic and visceral motor control, white fiber tracts ascend and descend
pneumotaxic and apneustic areas: help control respiration
nuclei and tracts linking cerebellum with brain stem, cerebrum and spinal cord
contains nuclei for cranial nerves V to VIII
Brain stem: medulla oblongata
Brain-spinal cord communication
Regulates autonomic functions
Cardio-respiratory center
Decussation of pyramid
Crossing over of motor tracts in medulla
R brain controls L side of body
Cerebellum
Compares intended movements to actual movements to smooth and coordinate complex, skilled movements
Regulates posture and balance
Cognition and language processing and problem solving
Arbor vitae = tree of life = white matter
Limbic System
A functional group involved in emotion, motivation, and emotional association with memory
Amygdala: aggression and fear
Cingulate gyrus: heart rate, BP, cognitive
Hippocampus: long term memories
Hypothalamus: ANS (hormone)
Mammillary bodies: formation of memory
Orbitofrontal cortex: decision making
What protects the brain?
Cranial bones
Cerebrospinal fluid
Cranial meninges
Cranial meninges
Pia mater, arachnoid mater, dura mater
subdural space, subarachnoid space
NO epidural space around brain
3 dural septa
extend inward and limit excessive movement of brain
falx cerebri: between cerebral hemispheres
tentorium cerebelli: separates cerebrum from cerebellum
falx cerebelli: seperates 2 cerebellar hemispheres
Cerebrospinal Fluid
clear, colorless fluid
cushions delicate brain tissues
optimal ionic concentrations for AP
transports (highly selective) glucose, proteins, ions and wastes
Choroid plexus
specialized ependymal cells + capillaries
secerete CSF into ventricles
~500 ml of CSF per day
4 Ventricles
For storage and recirculation of CSF
2 lateral ventricles separated by septum pellucidum
3rd ventricle: btwn right and left halves of thalamus
4th ventricle: btwn brain stem and cerebellum
Blood Brain Barrier
Protective mechanism that helps maintain stable environment for brain
Astrocytes supply signals to endothelial cells, causing them to make tight junctions
Parkinson’s Disease
Damage to basal ganglia, degeneration of dopamine-releasing neurons of substantia nigra
tremor, rigidity, involuntary muscle movements
Alzheimer’s Disease
Progressive degenerative disease of brain, resulting in dementia
Formation of senile plaques between neurons
Hydrocephaly
water in the brain
Blockage of drainage of CSF (tumor, inflammation, developmental malformation, meningitis, hemorrhage or injury)
Drain CSF by shunting to veins of neck/abdomen
Spinal cord
From foramen magnum to L2
Regions: cervical, thoracic, lumbar, sacral, coccygeal
31 pairs of spinal nerves
Not uniform in diameter (cervical enlargement, lumbar enlargement)
Conus medullaris
tapered inferior end of spinal cord
ends btwn L1 and L2
Cauda equina
Origin of spinal nerves extending inferiorly from conus medullaris
Meninges (spinal cord)
Dura mater: outermost
Arachnoid mater: thin and wispy
Pia mater: bound tightly to surface, forms filum terminale (anchors spinal cord to coccyx) and forms dentriculate ligaments that attach spinal cord to dura
Epidural space (spinal cord)
Filled with fat and network of veins
Subdural space (spinal cord)
Serous fluid
Subarachnoid space
Filled with CSF
Spinal Cord
Grey matter in its core, white matter outside
Flaccid paralysis
Caused by severe damage to ventral root or ventral horns
Nerve impulses do not reach the muscles served, they cannot move. Without stimulation, they atrophy
Spastic paralysis
Caused when only the upper motor neurons of the primary motor cortex are damaged
Spinal motor neurons remain intact, spinal reflex activity continues to stimulate muscles irregularly
Reticular formation
Extends through brain stem, keeps cortex alert via reticular activating system and dampening familiar, repetitive, or weak sensory inputs